Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma.

Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma. Research Abstract Details 

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Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma. Abstract Text:

Tetsuo Maeda,Ukihide Tateishi,Shigenobu Suzuki,Yasuaki Arai,E Edmund Kim,Kazuro Sugimura,

OBJECTIVE: The aim of the present study was to evaluate the value of magnetic resonance (MR) screening for detection of hepatic metastasis in patients with locally controlled choroidal melanoma. METHODS: MR examinations were performed after an initial diagnosis of choroidal melanoma in 159 patients (mean age 56 years: range, 10-86 years). The MR follow-up interval was 5.2 +/- 1.7 years (range, 1.2-6.6 years). A total of 363 MR studies were reviewed by two radiologists for predominant signal intensity characteristics. Hepatic metastasis was verified by histological examination: tumor resection and CT-guided needle biopsy specimens and/or on the basis of an obvious progression in number and/or size of the lesions on the follow-up MR examination. RESULTS: The majority of patients underwent MR examinations from one to three times (n = 126, 79%). During a mean follow-up period of 5.7 years, a focal abnormality in the liver was found in 20 patients (13%). Of these, 15 patients (9%) were diagnosed as having hepatic metastasis. The number of the metastatic lesions with a short T1 and short T2 pattern were one (n = 1, 9%), two (n = 2, 18%), three (n = 1, 9%) and multiple (n = 7, 63%). The focal abnormalities of MR examinations in five other patients consisted of vascular artifacts (n = 3, 15%) and cysts with hemorrhage (n = 2, 10%). CONCLUSIONS: The screening of MR examinations detected hepatic metastasis in 15 of 159 patients (9%) with locally controlled choroidal melanoma.

Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma. Publishing Authors By Initials

T Maeda,U Tateishi,S Suzuki,Y Arai,EE Kim,K Sugimura,

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Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Japanese journal of clinical oncology

VOLUME: 37

Page Numbers: 282-6

Journal Abbreviation: Jpn. J. Clin. Oncol.

ISSN: 1465-3621

DAY: 7

MONTH: Apr

YEAR: 2007

Magnetic resonance screening trial for hepatic metastasis in patients with locally controlled choroidal melanoma. Information

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LANGUAGE: eng

NlmUniqueID: 313225

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AFFILIATION: Division of Diagnostic Radiology, Cancer Center Hospital, Tokyo, Japan.

Country: Japan

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MEDLINETA: Jpn J Clin Oncol

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