Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells.

Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Research Abstract Details 

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Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Abstract Text:

OBJECTIVE: To study the mechanism and to measure the oxygenation/reduction activity of Ehrlich ascetic tumor cells in an isotonic solution by means of lucigenin dependent chemiluminescence. METHODS: All the measurements of the chemiluminescence redox activity of Ehrlich ascetic tumor cell samples in suspension medium, were carried out using a photon counting system especially designed to the purpose. The areas under the chemiluminescence kinetic curves were measured at different cell physiological conditions and at different agents concentrations effect. RESULTS: The rates of lucigenin chemiluminescence redox functional activity of Ehrlich ascetic tumor cells were significantly different from normal oxygenation/reduction activity at different physiological environments of Ehrlich ascetic tumor cells suspension conditions (i.e. cell membrane permeability changes, presence and absence of oxidative or reductive agents at different concentrations and oxy/hydroxy free radical protective agents). CONCLUSION: The results explain more fully the mechanism and the value of a lucigenin dependent chemiluminescence probe of the redox functional activity of Ehrlich ascetic tumor cells (at different physiological conditions of suspension).

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Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Saudi medical journal

VOLUME: 22

Page Numbers: 164-9

Journal Abbreviation: Saudi Med J

ISSN: 0379-5284

DAY: 23

MONTH: Feb

YEAR: 2001

Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Information

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LANGUAGE: eng

NlmUniqueID: 7909441

Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Keywords Mesh Terms:

KEYWORDS: Tumor Cells, Cultured

MESH TERMS: metabolism

Chemical & Substance for Abstract: Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells. Information

Substance Name: 10,10'-dimethyl-9,9'-biacridinium

Registry Number: 2315-97-1

Grant and Affiliation Information for Lucigenin chemiluminesence. A new approach to study the redox activity of Ehrlich ascetic tumor cells.

AFFILIATION: Department of Physiology and Medical Biophysics, University of Basrah, College of Medicine, Basrah, Iraq.

Country: Saudi Arabia

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MEDLINETA: Saudi Med J

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