Cogan's syndrome is a rare inflammatory disease characterized by nonsyphilitic ocular interstitial keratitis associated with hearing loss and vestibular impairment. Although systemic corticosteroids are usually used as the standard therapy, hearing ability in most cases gradually deteriorates. We, herein, describe a patient with childhood Cogan's syndrome who was treated with low-dose oral methotrexate, which successfully helped to taper the doses of the systemic corticosteroids. The serum levels of the complements were good markers for the disease activity in this patient.
Low-dose oral methotrexate for the management of childhood Cogan's syndrome: a case report. Publishing Authors By Initials
Low-dose oral methotrexate for the management of childhood Cogan's syndrome: a case report. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Clinical rheumatology
VOLUME: 26
Page Numbers: 2201-3
Journal Abbreviation:
ISSN: 0770-3198
DAY: 5
MONTH: 07
YEAR: 2007
Low-dose oral methotrexate for the management of childhood Cogan's syndrome: a case report. Information
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LANGUAGE: eng
NlmUniqueID: 8211469
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Grant and Affiliation Information for Low-dose oral methotrexate for the management of childhood Cogan's syndrome: a case report.
AFFILIATION: Department of Pediatrics, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuou-ku, Chiba city, Chiba, Japan, yuzaburo@graduate.chiba-u.jp.
Country: Belgium
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MEDLINETA: Clin Rheumatol
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