Long-term therapeutic outcome of acute primary angle closure in Japanese.

Long-term therapeutic outcome of acute primary angle closure in Japanese. Research Abstract Details 

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Long-term therapeutic outcome of acute primary angle closure in Japanese. Abstract Text:

Akira Sawada,Akira Aoyama,Tetsuya Yamamoto,Naoyoshi Takatsuka,Akira Sawada,Akira Aoyama,Tetsuya Yamamoto,Naoyoshi Takatsuka,Akira Sawada,Akira Aoyama,Tetsuya Yamamoto,Naoyoshi Takatsuka,

PURPOSE: To investigate the long-term clinical course of acute primary angle closure (APAC) and acute primary angle-closure glaucoma (APACG) in Japanese patients. METHODS: We retrospectively reviewed our records of 66 consecutive APAC or APACG eyes observed between February 1992 and December 2003 (mean follow-up, 42.1 months). Immediately after the diagnosis, all patients had received similar medications to halt the acute attack. Subsequently, laser iridotomy or surgical peripheral iridectomy and/or laser iridoplasty were conducted. If intraocular pressure (IOP) control was poor under maximum tolerable ocular hypotensive agents, trabeculectomy with adjunctive mitomycin C (MMC) was undertaken. RESULTS: After laser therapy, the probability of success, defined as an IOP of <21 mmHg with or without medications, was 81.2% +/- 6.2%. In the ten eyes that were trabeculectomized, the probability of success based on the same criterion was 40.0% +/- 29.7%. Multivariate analysis revealed that the degree of synechial angle closure (P = 0.029) and the preexistence of chronic glaucomatous optic neuropathy (P = 0.015) significantly influenced the need for subsequent filtering surgery. CONCLUSIONS: Without the intervention of filtering surgery, 84.6% of eyes with APAC or APACG maintained IOP control with or without antiglaucoma medications. However, APAC and APACG eyes that eventually received trabeculectomy were predisposed to an uncontrollable IOP, even with the intraoperative application of MMC. The severity of APAC or APACG in Japanese may be affected by an underlying creeping angle closure.

Long-term therapeutic outcome of acute primary angle closure in Japanese. Publishing Authors By Initials

A Sawada,A Aoyama,T Yamamoto,N Takatsuka,A Sawada,A Aoyama,T Yamamoto,N Takatsuka,A Sawada,A Aoyama,T Yamamoto,N Takatsuka,

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PUBMED ID PMID:

MEDLINE DATE: 2007 Sep-Oct

Long-term therapeutic outcome of acute primary angle closure in Japanese. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Japanese journal of ophthalmology

VOLUME: 51

Page Numbers: 353-9

Journal Abbreviation: Jpn. J. Ophthalmol.

ISSN: 0021-5155

DAY: 5

MONTH: 10

YEAR: 2007

Long-term therapeutic outcome of acute primary angle closure in Japanese. Information

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LANGUAGE: eng

NlmUniqueID: 44652

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Grant and Affiliation Information for Long-term therapeutic outcome of acute primary angle closure in Japanese.

AFFILIATION: Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan. sawadaa-gif@umin.ac.jp

Country: Japan

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MEDLINETA: Jpn J Ophthalmol

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