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Long-term results of tonsillectomy as a treatment for IgA nephropathy.

Long-term results of tonsillectomy as a treatment for IgA nephropathy. Research Abstract Details 

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  • Long-term results of tonsillectomy as a treatment for IgA nephropathy. Abstract Text:

    hirofumi akagiHirofumi Akagi,michiya kosakaMichiya Kosaka,kenshi hattoriKenshi Hattori,akira doiAkira Doi,kunihiro fukushimaKunihiro Fukushima,mitsuhiro okanoMitsuhiro Okano,shin kariyaShin Kariya,kazunori nishizakiKazunori Nishizaki,nobuyoshi sugiyamaNobuyoshi Sugiyama,kenichi shikataKenichi Shikata,hirofumi makinoHirofumi Makino,yu masudaYu Masuda,

    IgA nephropathy (IgAN) is the most common form of chronic glomerulonephritis with IgA deposits present mainly in the mesangial areas. We performed a 10-year retrospective case-control study of 71 patients with IgAN to evaluate the long-term effects and prognostic factors associated with tonsillectomy. Forty-one patients (19 males and 22 females) underwent tonsillectomy (Group A) and 30 patients (13 males and 17 females) did not (Group B). These patients were followed for more than 10 years after renal biopsy. The average age at initial renal biopsy was 29.78 years in Group A and 33.0 years in Group B. The average follow-up period was 13 years and 3 months in Group A, and 12 years and 7 months in Group B. Glomerular damage demonstrated on renal biopsy was more extensive in Group A than in Group B. Prognosis after 10 years of follow-up was compared between the two groups. The clinical remission rate was 24.4% in Group A and 13.3% in Group B, the stable renal function rate was 82.9% in Group A and 70.0% in Group B, and the renal survival rate was 95.1% in Group A and 73.3% in Group B. The renal survival rate in Group A was significantly higher than that in Group B (p <0.05). Although evaluation of renal pathology based on renal biopsy was useful in predicting the long-term effects of tonsillectomy in IgAN patients, the results of tonsillar provocation tests were not.

    Long-term results of tonsillectomy as a treatment for IgA nephropathy. Publishing Authors By Initials

    h akagiH Akagi,m kosakaM Kosaka,k hattoriK Hattori,a doiA Doi,k fukushimaK Fukushima,m okanoM Okano,s kariyaS Kariya,k nishizakiK Nishizaki,n sugiyamaN Sugiyama,k shikataK Shikata,h makinoH Makino,y masudaY Masuda,

    For similar surgical procedures, operative: otorhinolaryngologic surgical procedures: tonsillectomy research abstracts see: surgical procedures, operative: otorhinolaryngologic surgical procedures: tonsillectomy research

    PUBMED ID PMID:

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    Long-term results of tonsillectomy as a treatment for IgA nephropathy. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Acta oto-laryngologica. Supplementum

    VOLUME:

    Page Numbers: 38-42

    Journal Abbreviation:

    ISSN: 0365-5237

    DAY: 13

    MONTH: Dec

    YEAR: 2004

    Long-term results of tonsillectomy as a treatment for IgA nephropathy. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370355

    Long-term results of tonsillectomy as a treatment for IgA nephropathy. Keywords Mesh Terms:

    KEYWORDS: Tonsillectomy

    MESH TERMS: pathology

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    Grant and Affiliation Information for Long-term results of tonsillectomy as a treatment for IgA nephropathy.

    AFFILIATION: Department of Otolaryngology, National Hospital Organization Minami-Okayama Medical Center, Okayama, Japan. akagih@s-okayama.hosp.go.jp

    Country: Norway

    Norway Research PublicationNorway Research Publication

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    MEDLINETA: Acta Otolaryngol Suppl

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