Long-term outcomes of acute myeloid leukemia in adults in Pakistan.

Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Research Abstract Details 

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Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Abstract Text:

G N Kakepoto,I A Burney,S Zaki,S N Adil,M Khurshid,

OBJECTIVE: To describe the long-term outcomes of Acute Myeloid Leukemia (AML) and to study clinicopathological features at presentation, morphological subtypes and remission rates. METHODS: Demographic information, response to therapy and survival of patients (>14 years of age) admitted between January 1988 to August 1996 with acute myeloid leukaemia was retrieved and analysed. RESULTS: Seventy-four patients were admitted with a diagnosis of AML during the study period. There were 43 males and 31 females. Age ranged between 15 and 70 years with a mean age of 38 years. The most common presenting feature was fever (67.5%) and the morphological subtype according to French-American-British Group (FAB) criteria was M4. Fifty-five patients received treatment and were evaluable for response and outcomes. Thirty-six (65.4%) patients had complete remission. Sixteen (29.1%) died during the first 28 days after starting induction chemotherapy. The median survival was 11 months. Six (11%) patients (4 females, 2 males) are surviving beyond 4 years (long-term survivors). CONCLUSION: Our study suggests that the long-term outcomes of adults with AML are comparable to what has been reported in the literature for patients who do not receive bone marrow transplants.

Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Publishing Authors By Initials

GN Kakepoto,IA Burney,S Zaki,SN Adil,M Khurshid,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 52

Page Numbers: 482-6

Journal Abbreviation:

ISSN: 0030-9982

DAY: 12

MONTH: Oct

YEAR: 2002

Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7501162

Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: epidemiology

Chemical & Substance for Abstract: Long-term outcomes of acute myeloid leukemia in adults in Pakistan. Information

Substance Name: Etoposide

Registry Number: 33419-42-0

Grant and Affiliation Information for Long-term outcomes of acute myeloid leukemia in adults in Pakistan.

AFFILIATION: Department of Pathology, The Aga Khan University Hospital, Karachi.

Country: Pakistan

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MEDLINETA: J Pak Med Assoc

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