Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor response to various therapies, including plasmapheresis, corticosteroid, and tacrolimus. The patient was then treated with intravenous immunoglobulin (IVIG), and showed a good response that persisted over 20 months. The outcome of this case suggests that IVIG treatment may be an effective therapeutic option for anti-MuSK antibody-positive MG, with a potentially long-term effect.
Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis. Publishing Authors By Initials
Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Acta neurologica Scandinavica
VOLUME: 116
Page Numbers: 406-8
Journal Abbreviation: Acta Neurol. Scand.
ISSN: 0001-6314
DAY: 7
MONTH: Dec
YEAR: 2007
Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis. Information
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LANGUAGE: eng
NlmUniqueID: 370336
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Grant and Affiliation Information for Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis.
AFFILIATION: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa, Japan. ashibata@med.kanasawa-u.ac.jp
Country: Denmark
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MEDLINETA: Acta Neurol Scand
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