Location of the essential thiol of porcine liver cathepsin B.

Location of the essential thiol of porcine liver cathepsin B. Research Abstract Details 

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Location of the essential thiol of porcine liver cathepsin B. Abstract Text:

K Takahashi,M Isemura,T Ono,T Ikenaka,

Porcine liver cathepsin B, a thiol enzyme, exists in at least three forms. While Form III is a single chain polypeptide, two peptide chains with molecular weights of 258000 and 4,000 are noncovalently bound together in Form I and Form II. The present study showed that aminoterminal sequences of Form III and the 4,000-dalton peptide isolated form Form II are identical. The 4,000-dalton peptide contained three cysteine or half-cystine residues, one of which was demonstrated to be essential for the enzyme activity by an incorporation study with [14C]iodoacetate. It was also shown that the 4,000-dalton peptide of the activated enzyme contained one cysteine and one cystine residue.

Location of the essential thiol of porcine liver cathepsin B. Publishing Authors By Initials

K Takahashi,M Isemura,T Ono,T Ikenaka,

For similar animals: chordata: vertebrates: mammals: artiodactyla: swine research abstracts see: animals: chordata: vertebrates: mammals: artiodactyla: swine research

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Location of the essential thiol of porcine liver cathepsin B. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 87

Page Numbers: 347-50

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jan

YEAR: 1980

Location of the essential thiol of porcine liver cathepsin B. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Location of the essential thiol of porcine liver cathepsin B. Keywords Mesh Terms:

KEYWORDS: Swine

MESH TERMS: analysis

Chemical & Substance for Abstract: Location of the essential thiol of porcine liver cathepsin B. Information

Substance Name: Cathepsins

Registry Number: EC 3.4.-

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Country: JAPAN

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MEDLINETA: J Biochem

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