Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates.

Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Research Abstract Details 

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Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Abstract Text:

Padmasana Singh,Amitabh Krishna,Rajagopala Sridaran,

GnRH I and its receptors have been demonstrated in the ovaries of various vertebrates, but their physiological significance in reproductive cascade is fragmentary. Bradykinin is a potent GnRH stimulator in the hypothalamus. In the present study, the presence of GnRH I and its receptor, and bradykinin and its receptor in the ovaries of non-mammalian vertebrates were investigated to understand their physiological significance. GnRH I immunoreactivity in the ovaries of fish, frog, reptile and bird were mainly found in the oocyte of early growing follicles and granulosa cells and theca cells of previtellogenic follicles. Vitellogenic follicles showed mild GnRH immunoreactivity. GnRH I-receptor and bradykinin were localized in the same cell types of the ovaries of these vertebrates. The presence of GnRH I, GnRH I-receptor and bradykinin in the ovaries of these vertebrates was confirmed by immunoblotting. The presence of GnRH I mRNA was demonstrated in the ovary of vertebrates using RT-PCR. The ovaries of reptiles and birds showed significantly higher intensity of immunoreactivity for GnRH I-receptor as compared with the fish and amphibian. This may have a correlation with the higher yolk content in the ovary of reptile and bird. These results suggest the possibility of GnRH I and bradykinin as important regulators of follicular development and vitellogenesis in the vertebrate ovary.

Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Publishing Authors By Initials

P Singh,A Krishna,R Sridaran,

For similar animals: chordata: vertebrates research abstracts see: animals: chordata: vertebrates research

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Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Reproduction (Cambridge, England)

VOLUME: 133

Page Numbers: 969-81

Journal Abbreviation: Reproduction

ISSN: 1470-1626

DAY: 3

MONTH: May

YEAR: 2007

Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100966036

Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Keywords Mesh Terms:

KEYWORDS: Vertebrates

MESH TERMS: metabolism

Chemical & Substance for Abstract: Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates. Information

Substance Name: Bradykinin

Registry Number: 58-82-2

Grant and Affiliation Information for Localization of gonadotrophin-releasing hormone I, bradykinin and their receptors in the ovaries of non-mammalian vertebrates.

AFFILIATION: Department of Zoology, Banaras Hindu University, Varanasi, India.

Country: England

AGENCY: United States NCRR

GRANT: RR03034

ACRONYM: RR

MEDLINETA: Reproduction

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