Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia.

Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia. Research Abstract Details 

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Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia. Abstract Text:

Duk Hyun Sung,Joon Young Choi,Du-Hwan Kim,Eun-Sang Kim,Young-Ik Son,Young-Seok Cho,Su Jin Lee,Kyung-Han Lee,Byung-Tae Kim,Duk Hyun Sung,Joon Young Choi,Du-Hwan Kim,Eun-Sang Kim,Young-Ik Son,Young-Seok Cho,Su Jin Lee,Kyung-Han Lee,Byung-Tae Kim,

The purpose of this study was to investigate whether (18)F-FDG PET/CT is useful for localizing dystonic cervical muscles in patients with idiopathic cervical dystonia (ICD) by comparing disease severity before and disease severity after botulinum toxin (BT) injection into hypermetabolic muscles. METHODS: Six patients with ICD underwent (18)F-FDG PET/CT. Dystonic muscles suitable for BT injection therapy were defined as those showing diffusely increased (18)F-FDG uptake. RESULTS: Hypermetabolic cervical muscles were identified in all 6 patients. In 2 patients who underwent PET/CT both in a supine position and in a sitting position during (18)F-FDG uptake, abnormal hypermetabolic muscles were observed by PET/CT only when patients were in the sitting position with their heads and necks in the adopted abnormal involuntary posture. Symptoms were significantly improved in 4 patients who underwent BT injection therapy guided by PET/CT and who were clinically monitored. CONCLUSION: (18)F-FDG PET/CT is potentially useful for identifying dystonic cervical muscles for BT therapy in patients with ICD.

Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia. Publishing Authors By Initials

DH Sung,JY Choi,DH Kim,ES Kim,YI Son,YS Cho,SJ Lee,KH Lee,BT Kim,DH Sung,JY Choi,DH Kim,ES Kim,YI Son,YS Cho,SJ Lee,KH Lee,BT Kim,

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Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of nuclear medicine : official publication

VOLUME: 48

Page Numbers: 1790-5

Journal Abbreviation: J. Nucl. Med.

ISSN: 0161-5505

DAY: 17

MONTH: 10

YEAR: 2007

Localization of dystonic muscles with 18F-FDG PET/CT in idiopathic cervical dystonia. Information

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LANGUAGE: eng

NlmUniqueID: 217410

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AFFILIATION: Department of Physical Medicine and Rehabilitation, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Country: United States

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MEDLINETA: J Nucl Med

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