Localization of antigenic determinants in the polypeptide chains of collagen.

Localization of antigenic determinants in the polypeptide chains of collagen. Research Abstract Details 

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Localization of antigenic determinants in the polypeptide chains of collagen. Abstract Text:

D Michaeli,G R Martin,J Kettman,E Benjamini,D Y Leung,B A Blatt,

After being injected with collagen from rat or guinea pig skin, rabbits form high titer, species-specific antibodies to collagen. Antibody is directed primarily against the alpha2 chain of collagen with little reaction with the alpha1 chain. The amino terminal peptide of cyanogen bromide cleavage of the alpha2 chain of guinea pig skin collagen, alpha2-CBl, effectively inhibited the antigen-antibody reaction, an indication that a major antigenic determinant of collagen is located at the amino terminal of the alpha2 chain.

Localization of antigenic determinants in the polypeptide chains of collagen. Publishing Authors By Initials

D Michaeli,GR Martin,J Kettman,E Benjamini,DY Leung,BA Blatt,

For similar biological phenomena, cell phenomena, and immunity: immunity: antibody specificity: species specificity research abstracts see: biological phenomena, cell phenomena, and immunity: immunity: antibody specificity: species specificity research

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Localization of antigenic determinants in the polypeptide chains of collagen. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Science (New York, N.Y.)

VOLUME: 166

Page Numbers: 1522-4

Journal Abbreviation: Science

ISSN: 0036-8075

DAY: 19

MONTH: Dec

YEAR: 1969

Localization of antigenic determinants in the polypeptide chains of collagen. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 404511

Localization of antigenic determinants in the polypeptide chains of collagen. Keywords Mesh Terms:

KEYWORDS: Species Specificity

MESH TERMS: chemistry

Chemical & Substance for Abstract: Localization of antigenic determinants in the polypeptide chains of collagen. Information

Substance Name: Collagen

Registry Number: 9007-34-5

Grant and Affiliation Information for Localization of antigenic determinants in the polypeptide chains of collagen.

AFFILIATION: Laboratory of Medical Entomology, Kaiser Foundation Research Institute, San Francisco, California, USA.

Country: United States

AGENCY: United States NIADDK

GRANT: AM 12234

ACRONYM: AM

MEDLINETA: Science

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