Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study.

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Abstract Text:

A reversed-phase liquid chromatography method for nicarbazin in broiler feeds and premixtures was developed, validated, and interlaboratory studied. The extraction solvent was an acetonitrile-methanol (1 + 1) mixture. For feedingstuffs, water was also added. The 4,4'-dinitrocarbanilide moiety of nicarbazin was detected at a wavelength of 350 nm. Recovery was > or =87%. At 20 mg/kg, the repeatability was 0.7% and the within-laboratory reproducibility was 2.7%. The limit of determination was <20 mg/kg. Other feed additives did not interfere in the assay that proved to be applicable to broiler feeds from different European Union countries. In an interlaboratory study, 4 positive broiler feeds, 1 blank pig feed, and 1 broiler premixture were analyzed by 19 laboratories using the method developed in this study. The relative standard deviation for repeatability (RSDr) of the feedingstuffs (20-240 mg/kg) varied between 2.6 and 10.2%. The HORRAT ranged between 0.70 and 1.22. Recoveries were 91-108%. Three laboratories detected small signals in the blind blank samples, ranging from 0.4 to 2 mg/kg. For the premixture, acceptable results for reproducibility could only be obtained after the sample weight and volume of extraction had been doubled. To avoid excessive dilution of the extracts, the range of the calibration curve had also been doubled. With this modified method, the RSDr was 5.7% and the HORRAT was 1.95 (10 laboratories).

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Publishing Authors By Initials

For similar natural sciences: physics: acoustics: ultrasonics research abstracts see: natural sciences: physics: acoustics: ultrasonics research

PUBMED ID PMID:

MEDLINE DATE:

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of AOAC International

VOLUME: 87

Page Numbers: 1269-77

Journal Abbreviation: J AOAC Int

ISSN: 1060-3271

DAY: 17

MONTH: 03

YEAR: 2008

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9215446

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Keywords Mesh Terms:

KEYWORDS: Ultrasonics

MESH TERMS: analysis

Chemical & Substance for Abstract: Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study. Information

Substance Name: Nicarbazin

Registry Number: 330-95-0

Grant and Affiliation Information for Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study.

AFFILIATION: RIKILT-Institute of Food Safety, Wageningen, The Netherlands. jacob.dejong@wur.nl

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J AOAC Int

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study Related Publications

• A case of two different tumors in the heart of a dog.
• Acceptance test of a commercially available software for automatic image registration of computed tomography (CT), magnetic resonance imaging (MRI) and 99mTc-methoxyisobutylisonitrile (MIBI) single-photon emission computed tomography (SPECT) brain images.
• An embedded optical nanowire loop resonator refractometric sensor.
• Correlation between induction of DNA fragmentation in lung cells from rats and humans and carcinogenic activity.
• Cortical white-matter microstructure in schizophrenia. Diffusion imaging study.
• Decreased entorhinal cortex volumes in schizophrenia.
• GABAergic function in detoxified heroin addicts: relationship to anxiety disorders.
• Human amnion: cytology and cell culture.
• Increased fronto-temporal perfusion in bipolar disorder.
• Is there a neurobiological basis of insight in schizophrenia?
• Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study.
• Lung carcinomas with a basaloid pattern: a study of 90 cases focusing on their poor prognosis.
• Management and outcomes of hepatic cirrhosis: Findings from the RING study.
• Neuroendocrine correlates of depression in abstinent heroin-dependent subjects.
• Neurotransmitter-neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable.
• Outcome after endografting in small and large abdominal aortic aneurysms: a metanalysis.
• Percutaneous treatment of a single saphenous vein graft with two different protection devices.
• Primary adrenocortical sarcomatoid carcinoma: case report and review of literature.
• Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression.
• Serotonin function in detoxified heroin abusers: prolactin and cortisol responses to fenfluramine challenge.
• Simultaneous determination of Zilpaterol and other beta agonists in calf eye by gas chromatography/tandem mass spectrometry.
• Social cognition, schizophrenia and brain imaging.
• Tissue plasminogen activator to prevent central venous access device infections: a systematic review of central venous access catheter thrombosis, infection and thromboprophylaxis.
• [Effects of high ergotamine doses on development of Galliera sarcoma.]
• [Latex risk prevention in San Paolo Hospital in Milan]
• [Not Available.]
• [Pathophysiology and prevention of contrast-induced acute renal.]
• [Sepsis, acute renal failure and multiple organ dysfunction syndrome.]
• [Stimulate creativity by discovering oneself and communicating with others. Stimulation as a therapeutic instrument]
• [The city and clerics]