Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin.

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Abstract Text:

J Sunamoto,K Iwamoto,H Kondo,S Shinkai,

Induced aggregation of multilamellar liposomes of egg lecithin with several polysaccharides, such as pullulan, dextran, hydroxyethylstarch, and amylopectin, has been investigated in conjunction with structural characteristics of polysaccharides, incubation temperature, ionic strength, and surface charge of liposomes. Aggregation of liposomes as a function of time was followed by monitoring turbidity of the liposome suspension at 600 nm. The inverse relationship between the minimal concentration and molecular weight of polysaccharides for the induced aggregation of liposomes was observed for all the polysaccharides employed. Polysaccharides having larger excluded volume more easily bind to liposomes, leading to the acceleration of the aggregation of liposomes. Hence, the order of efficiency of polysaccharides for the promotion of liposome aggregation was pullulan greater than dextran greater than hydroxyethylstarch congruent to amylopectin. Increasing the surface charge of liposomes brought about a decrease in aggregation irrespective of the sign. Even when negatively charged liposomes were incubated with the cationic DEAE-dextran, the liposome aggregation was depressed. These results including salt effect and temperature dependency of the induced aggregation of liposomes supported a plausible mechanism for the reaction, the polysaccharide-bridging mechanism, which has been provided for the polysaccharide-promoted agglutination of human erythrocytes.

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Publishing Authors By Initials

J Sunamoto,K Iwamoto,H Kondo,S Shinkai,

For similar environment and public health: environment: environment, controlled: temperature research abstracts see: environment and public health: environment: environment, controlled: temperature research

PUBMED ID PMID:

MEDLINE DATE:

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 88

Page Numbers: 1219-26

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Nov

YEAR: 1980

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Keywords Mesh Terms:

KEYWORDS: Temperature

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin. Information

Substance Name: Polysaccharides

Registry Number: 0

Grant and Affiliation Information for Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin.

AFFILIATION:

Country: JAPAN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Biochem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Liposomal membranes VI Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin Related Publications

• A coordination gelator that shows a reversible chromatic change and sol-gel phase-transition behavior upon oxidative/reductive stimuli.
• A stable single piece of unimolecularly pi-stacked porphyrin aggregate in a thixotropic low molecular weight gel: a one-dimensional molecular template for polydiacetylene wiring up to several tens of micrometers in length.
• Absence of re-epithelialization in a fatal case of toxic epidermal necrolysis: is hyperbilirubinemia a culprit?
• Age-related changes in prolactin secretion and the population of mammotrophs in the rat: A longitudinal study.
• Angle-controlled arrangement of single-walled carbon nanotubes solubilised by 8-quinolinol metal chelate derivatives on mica.
• Complex formation between cationic beta-1,3-glucan and hetero-sequence oligodeoxynucleotide and its delivery into macrophage-like cells to induce cytokine secretion.
• Creation of a mixed-valence state from one-dimensionally aligned TTF utilizing the self-assembling nature of a low molecular-weight gel.
• Creation of polynucleotide-assisted molecular assemblies in organic solvents: general strategy toward the creation of artificial DNA-like nanoarchitectures.
• Cumulative effect of disinfection procedures on microhardness and tridimensional stability of a poly(methyl methacrylate) denture base resin.
• Distinct Roles of TRF1 in the Regulation of Telomere Structure and Lengthening.
• Extracellular matrix 22-kDa protein interacts with decorin core protein and is expressed in cutaneous fibrosis.
• Functional identification of an anti-sigma(E) factor from Thermus thermophilus HB8.
• G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.
• Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator.
• Hierarchical carbon nanotube assemblies created by sugar-boric or boronic acid interactions.
• Histone H1 variant, H1R is involved in DNA damage response.
• Liposomal membranes. VI. Polysaccharide-induced aggregation of multilamellar liposomes of egg lecithin.
• Molecular dynamics studies of side chain effect on the beta-1,3-D-glucan triple helix in aqueous solution.
• Primary stability of turned and acid-etched screw-type implants: a removal torque and histomorphometric study in rabbits.
• Purification and characterization of subcomponent Clq of the first component of bovine complement.
• Self-assembly of supramolecular chiral insulated molecular wire.
• Sol-gel reaction of porphyrin-based superstructures in the organogel phase: creation of mechanically reinforced porphyrin hybrids.
• Systemic lupus erythematosus with lichen planus-like eruptions associated with pericarditis.
• X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7.
• [60]fullerene-motivated organogel formation in a porphyrin derivative bearing programmed hydrogen-bonding sites.
• [Intrapleural chemotherapy-current status and problems in Japan.]
• [Regulatory factors for images of the elderly among elementary school students assessed through secular trend analyses by frequency of inter-exchange with "REPRINTS" senior volunteers]