LIN-12/Notch signaling in C. elegans.

LIN-12/Notch signaling in C. elegans. Research Abstract Details 

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LIN-12/Notch signaling in C. elegans. Abstract Text:

Iva Greenwald,Iva Greenwald,Iva Greenwald,

Receptors of the LIN-12/Notch family mediate cell-cell interactions during animal development, and aberrations in LIN-12/Notch signaling have been implicated in human disease. Studies in C. elegans have been instrumental in defining the basic features of the LIN-12/Notch pathway, the role of LIN-12/Notch proteins as receptors for intercellular signals, the mechanism of signal transduction, and the regulation of LIN-12/Notch signaling during cell fate decisions. This chapter is focused on detailing how the "awesome power of C. elegans genetics" has identified many core components and modulators of LIN-12/Notch activity.

LIN-12/Notch signaling in C. elegans. Publishing Authors By Initials

I Greenwald,I Greenwald,I Greenwald,

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LIN-12/Notch signaling in C. elegans. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: WormBook : the online review of C. elegans biology

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Page Numbers: 1-16

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ISSN: 1551-8507

DAY: 8

MONTH: 08

YEAR: 2005

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LANGUAGE: eng

NlmUniqueID: 101303985

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AFFILIATION: Howard Hughes Medical Institute and Department of Biochemistry and Molecular Biophysics, Columbia University, College of Physicians and Surgeons, New York, New York 10032 USA. greenwald@cancercenter.columbia.edu.

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MEDLINETA: WormBook

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