Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice.

Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Research Abstract Details 

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Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Abstract Text:

Katsuhiko Sakamoto,Koji Kadota,Katsutaka Oishi,

In the present study, we investigated the effect of fasting on photoentrainment of the peripheral circadian oscillator in the mammalian heart. Northern blotting showed that a single light pulse applied at an appropriate time in constant darkness, caused obvious phase-shifting in the circadian expression rhythm of the mammalian clock gene Period2 (mPer2) even in the hearts of food-deprived mice. Fasting did not significantly affect either the phase or the light-induced phase-shifts of the mPer2 rhythm. Although several studies of temporal feeding restriction have indicated that feeding is the dominant timing cue for mammalian peripheral oscillators, our findings suggest that feeding is not essential for mammals to induce phase resetting of the circadian oscillator in the heart.

Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Publishing Authors By Initials

K Sakamoto,K Kadota,K Oishi,

For similar proteins: transcription factors research abstracts see: proteins: transcription factors research

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Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental animals / Japanese Association for La

VOLUME: 53

Page Numbers: 471-4

Journal Abbreviation: Exp. Anim.

ISSN: 1341-1357

DAY: 19

MONTH: Oct

YEAR: 2004

Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Information

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LANGUAGE: eng

NlmUniqueID: 9604830

Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: metabolism

Chemical & Substance for Abstract: Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice. Information

Substance Name: Transcription Factors

Registry Number: 0

Grant and Affiliation Information for Light-induced phase-shifting of the peripheral circadian oscillator in the hearts of food-deprived mice.

AFFILIATION: Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310-1495, USA.

Country: Japan

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MEDLINETA: Exp Anim

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