Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner.

Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Research Abstract Details 

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Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Abstract Text:

Y Okamoto,T Sekine,

It was shown that the heavy chain structure was altered by the phosphorylation of light chain in gizzard myosin. Phosphorylated myosin was compared with unphosphorylated myosin with respect to the chymotryptic fragmentation with or without ATP in the medium. The rise and fall of the fragments were well explained by the reconstitution model for unphosphorylated myosin (Okamoto, Y., et al. (1980) J. Biochem. 88, 361-371). A specific cleavable site in the myosin head was completely abolished by the phosphorylation of light chain. The effect of phosphorylation on the site could be observed in the absence of ATP but not in its presence. These results strongly suggest the possible integrity of the site, 5K daltons apart from the masked N terminus, for the physiological activity of gizzard myosin.

Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Publishing Authors By Initials

Y Okamoto,T Sekine,

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: molecular conformation: protein conformation research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: molecular conformation: protein conformation research

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Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 89

Page Numbers: 697-700

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Feb

YEAR: 1981

Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Keywords Mesh Terms:

KEYWORDS: Protein Conformation

MESH TERMS: analysis

Chemical & Substance for Abstract: Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner. Information

Substance Name: Myosins

Registry Number: EC 3.6.1.4

Grant and Affiliation Information for Light chain phosphorylation alters the N terminal structure of gizzard myosin heavy chain in an ATP dependent manner.

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Country: JAPAN

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MEDLINETA: J Biochem

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