Life stress and the course of early-onset bipolar disorder.

Life stress and the course of early-onset bipolar disorder. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Life stress and the course of early-onset bipolar disorder. Abstract Text:

Eunice Y Kim,David J Miklowitz,Adrine Biuckians,Kimberley Mullen,Eunice Y Kim,David J Miklowitz,Adrine Biuckians,Kimberley Mullen,

BACKGROUND: Studies of adult bipolar patients and adolescents with major depression indicate that life stress and mood symptoms are temporally and causally related to one another. This study examined whether levels of life stress predict levels of mood symptoms among bipolar adolescents participating in a treatment development study of family-focused psychoeducation and pharmacotherapy. METHODS: Bipolar adolescents (n=38) who reported a period of acute mood symptoms within the prior 3 months were recruited for a 1-year study of life stress. Clinician-administered evaluations were completed with adolescents and parents at 3-month intervals for up to 12 months, using the UCLA Life Stress Interview and the K-SADS Mania and Depression Rating Scales. RESULTS: Chronic stress in family, romantic and peer relationships was associated with less improvement in mood symptoms over the study year. The frequency of severe, independent life events also predicted less improvement in mood symptoms. Higher levels of chronic stress in family and romantic relationships, and higher severity of independent events, were more strongly associated with mood symptoms among older adolescents. Results were independent of adolescents' psychosocial treatment regimens. LIMITATIONS: The majority of adolescents received family-focused psychoeducational treatment and all were being treated with psychotropic medication. The influence of life stress on mood symptoms may have been attenuated by intensive intervention. CONCLUSIONS: Stress is linked to changes in mood symptoms among bipolar adolescents, although correlations between life events and symptoms vary with age. Chronic stress in family, romantic, and peer relationships are important targets for psychosocial intervention.

Life stress and the course of early-onset bipolar disorder. Publishing Authors By Initials

EY Kim,DJ Miklowitz,A Biuckians,K Mullen,EY Kim,DJ Miklowitz,A Biuckians,K Mullen,

For similar behavioral disciplines and activities: psychotherapy: psychotherapy, brief research abstracts see: behavioral disciplines and activities: psychotherapy: psychotherapy, brief research

PUBMED ID PMID:

MEDLINE DATE:

Life stress and the course of early-onset bipolar disorder. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of affective disorders

VOLUME: 99

Page Numbers: 37-44

Journal Abbreviation:

ISSN: 0165-0327

DAY: 7

MONTH: 11

YEAR: 2006

Life stress and the course of early-onset bipolar disorder. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7906073

Life stress and the course of early-onset bipolar disorder. Keywords Mesh Terms:

KEYWORDS: Psychotherapy, Brief

MESH TERMS: therapy

Chemical & Substance for Abstract: Life stress and the course of early-onset bipolar disorder. Information

Substance Name: Antimanic Agents

Registry Number: 0

Grant and Affiliation Information for Life stress and the course of early-onset bipolar disorder.

AFFILIATION: University of Colorado, Boulder, CO, USA. eykim@mednet.ucla.edu

Country: Netherlands

AGENCY: United States NIMH

GRANT: MH62555

ACRONYM: MH

MEDLINETA: J Affect Disord

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Life stress and the course of early-onset bipolar disorder Related Publications

• "Bridge to decision"--time to consider an additional management paradigm.
• 12-year outcomes following permanent prostate brachytherapy in patients with clinically localized prostate cancer.
• A new archival approach to the study of values and value--Behavior relations: Validation of the value lexicon.
• Addition of CpG ODN to recombinant Pseudomonas aeruginosa ExoProtein A conjugates of AMA1 and Pfs25 greatly increases the number of responders.
• Analysis of triacetone triperoxide (TATP) and TATP synthetic intermediates by electrospray ionization mass spectrometry.
• Balloon assessment of patent foramen ovale morphology and the modification of tunnels using a balloon detunnelisation technique.
• Caloric requirements in total parenteral nutrition.
• Dangerous and severe personality disorder and in need of treatment.
• Drug Enforcement Administration and its relationship to JCAH.
• Effect of endovascular stenting of aortic coarctation on biventricular function in adults.
• Engineering plant oils as high-value industrial feedstocks for biorefining: the need for underpinning cell biology research.
• Enzymatic hydrolysis of organic waste materials in a solid-liquid system.
• Epididymal P34H protein deficiency in men evaluated for infertility.
• Factors in pregnancy affecting the newborn.
• Health professionals' and primary producers' understanding of sustainable food production systems for healthy eating.
• Hematopoietic stem cell recipients do not develop post-transplantation immune tolerance to antigens present on minimal residual disease.
• High-Risk Acute Lymphoblastic Leukemia Cells with bcr-abl and Ink4a/Arf Mutations Retain Susceptibility to Alloreactive T Cells.
• Is the inhibitory control test as accurate as standard psychometric testing for diagnosing hepatic encephalopathy?
• Life stress and the course of early-onset bipolar disorder.
• Mapping the ethical frontiers for patents in biotechnology.
• Nutritional assessment in the seriously ill patient.
• Papillary fibroelastoma of the tricuspid valve.
• Phosphomonesterase in bull semen.
• Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era.
• Roentgenologic aspects of lethal granulomatous ulceration of the midline facial tissues.
• Soil quality and barley growth as influenced by the land application of two compost types.
• The effect of lactate infusion on myocardial metabolism and ventricular function following ischemia and cardioplegia.
• The role of hepatic encephalopathy in the era of MELD.
• Trichobezoar: survival following complication of perforated ulcer.
• Videoconferencing and forensic mental health in Australia.