Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams.

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Abstract Text:

B Bocca,G Forte,F Petrucci,A Cristaudo,

It is extensively well-known that Ni and other metals occurring as impurities in cosmetic products might give rise to contact dermatitis in subjects with pre-existing allergy. The present study on the content of 13 metals (Cd, Co, Cr, Cu, Hg, Ir, Mn, Ni, Pb, Pd, Pt, Rh, and V) in moisturizing creams, labelled as "Ni-tested" (i.e., Ni content <100 ng g(-1)) and available on the Italian market, provides a basis for assessing their safety for consumers. Quantification of metals was performed by sector field inductively coupled plasma mass spectrometry after microwave-assisted acid digestion of products. The developed method had limits of quantification less than 0.8 ng g(-1) for all the elements; recovery was in the interval 88% (Cd, Co) to 110% (Hg), and precision was always under 7%. Nickel was present in all the products with levels between 17.5 and 153 ng g(-1); three skin creams were slightly above the concentration reported on the label. The other elements were at levels below 1 microg g(-1). The highest concentrations, in ng g(-1), of Co, Cr, Cu, and Mn were 222, 303, 51.2, and 59.9, respectively. Mean Cd, Pb, and V were below 5 ng g(-1), while Hg was absent in all the samples. Among the new emergent allergens, Ir and Rh were in traces or even undetectable, while Pt had levels of 2.65 and 6.28 ng g(-1) in two creams and Pd was equal to 1.07 ng g(-1) in one product. The overall results are below the sensitizing limit proposed for consumer products and, thus, probably have no significant toxicological effects. Nevertheless, some creams presented amounts of Co and Cr comparable to those of Ni and therefore they have to be monitored in consideration of their cross-reactivity as well.

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Publishing Authors By Initials

B Bocca,G Forte,F Petrucci,A Cristaudo,

For similar therapeutics: hygiene: skin care research abstracts see: therapeutics: hygiene: skin care research

PUBMED ID PMID:

MEDLINE DATE:

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of pharmaceutical and biomedical analysis

VOLUME: 44

Page Numbers: 1197-202

Journal Abbreviation:

ISSN: 0731-7085

DAY: 3

MONTH: 05

YEAR: 2007

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8309336

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Keywords Mesh Terms:

KEYWORDS: Skin Care

MESH TERMS: methods

Chemical & Substance for Abstract: Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. Information

Substance Name: Aconitate Hydratase

Registry Number: EC 4.2.1.3

Grant and Affiliation Information for Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams.

AFFILIATION: Istituto Superiore di Sanità, Department of Environment and Primary Prevention, Viale Regina Elena 299, 00161 Rome, Italy.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Pharm Biomed Anal

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams Related Publications

• A pilot study on the content and the release of Ni and other allergenic metals from cheap earrings available on the Italian market.
• Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams.
• Nickel, palladium and rhodium induced IFN-gamma and IL-10 production as assessed by in vitro ELISpot-analysis in contact dermatitis patients.
• [Evaluation of a series of serum mesothelin in patients with pleural malignant mesothelioma]
• [Management of latex allergy in the Pisa University Hospital: analysis of data deriving from the Registry filing both allergic patients and employees]
• [Medical surveillance of previously asbestos-exposed workers: report of a case of lung cancer with high level of serum mesothelin]
• [Serum mesothelin dosages in follow-up of previously exposed workers]