Leukemia inhibitory factor (LIF) and its biological activity.

Leukemia inhibitory factor (LIF) and its biological activity. Research Abstract Details 

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Leukemia inhibitory factor (LIF) and its biological activity. Abstract Text:

Grazyna Chodorowska,Anna G?owacka,Ma?gorzata Tomczyk,

Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It shows a wide range of biologic activities that include the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. LIF has potent proinflammatory property, being the inducer of the acute phase protein synthesis and affecting the cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic and neuronal cells. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origin.

Leukemia inhibitory factor (LIF) and its biological activity. Publishing Authors By Initials

G Chodorowska,A G?owacka,M Tomczyk,

For similar endocrine system: neurosecretory systems research abstracts see: endocrine system: neurosecretory systems research

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Leukemia inhibitory factor (LIF) and its biological activity. Journal Published:

PUBLICATION TYPE: Review

Journal: Annales Universitatis Mariae Curie-Sk?odowska. Sec

VOLUME: 59

Page Numbers: 189-93

Journal Abbreviation:

ISSN: 0066-2240

DAY: 21

MONTH: 01

YEAR: 2004

Leukemia inhibitory factor (LIF) and its biological activity. Information

Number of References: 15

LANGUAGE: eng

NlmUniqueID: 414101

Leukemia inhibitory factor (LIF) and its biological activity. Keywords Mesh Terms:

KEYWORDS: Neurosecretory Systems

MESH TERMS: physiology

Chemical & Substance for Abstract: Leukemia inhibitory factor (LIF) and its biological activity. Information

Substance Name: Leukemia Inhibitory Factor

Registry Number: 0

Grant and Affiliation Information for Leukemia inhibitory factor (LIF) and its biological activity.

AFFILIATION: Chair and Department of Dermatology, Skubiszewski Medical University of Lublin.

Country: Poland

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MEDLINETA: Ann Univ Mariae Curie Sklodows

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