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Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury.

Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Research Abstract Details 

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  • Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Abstract Text:

    james f zacharyJames F Zachary,james p blueJames P Blue,rita j millerRita J Miller,brian j ricconiBrian J Ricconi,j gary edenJ Gary Eden,william d o'brienWilliam D O'Brien,

    Thermal injury, a potential mechanism of ultrasound-induced lung hemorrhage, was studied by comparing lesions induced by an infrared laser (a tissue-heating source) with those induced by pulsed ultrasound. A 600-mW continuous-wave CO2 laser (wavelength approximately 10.6 microm) was focused (680-microm beamwidth) on the surface of the lungs of rats for a duration between 10 to 40 s; ultrasound beamwidths were between 310 and 930 microm. After exposure, lungs were examined grossly and then processed for microscopic evaluation. Grossly, lesions induced by laser were somewhat similar to those induced by ultrasound; however, microscopically, they were dissimilar. Grossly, lesions were oval, red to dark red and extended into subjacent tissue to form a cone. The surface was elevated, but the center of the laser-induced lesions was often depressed. Microscopically, the laser-induced injury consisted of coagulation of tissue, cells and fluids, whereas injury induced by ultrasound consisted solely of alveolar hemorrhage. These results suggest that ultrasound-induced lung injury is most likely not caused by a thermal mechanism.

    Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Publishing Authors By Initials

    jf zacharyJF Zachary,jp blueJP Blue,rj millerRJ Miller,bj ricconiBJ Ricconi,jg edenJG Eden,wd o'brienWD O'Brien,

    For similar therapeutics: hyperthermia, induced: diathermy: ultrasonic therapy research abstracts see: therapeutics: hyperthermia, induced: diathermy: ultrasonic therapy research

    PUBMED ID PMID:

    MEDLINE DATE:

    Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Journal Published:

    PUBLICATION TYPE: Research Support, N.I.H., Extr

    Journal: Ultrasound in medicine & biology

    VOLUME: 32

    Page Numbers: 1763-70

    Journal Abbreviation:

    ISSN: 0301-5629

    DAY: 3

    MONTH: Nov

    YEAR: 2006

    Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 410553

    Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Keywords Mesh Terms:

    KEYWORDS: Ultrasonic Therapy

    MESH TERMS: adverse effects

    Chemical & Substance for Abstract: Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury. Information

    Substance Name:

    Registry Number:

    Grant and Affiliation Information for Lesions of ultrasound-induced lung hemorrhage are not consistent with thermal injury.

    AFFILIATION: Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA. zacharyj@uiuc.edu

    Country: England

    England Research PublicationEngland Research Publication

    AGENCY: United States NIBIB

    GRANT: R37EB02641

    ACRONYM: EB

    MEDLINETA: Ultrasound Med Biol

    REFSOURCE:

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    ACCESSION NUMBER:

    Number Hits: 0

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