Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1.

Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Research Abstract Details 

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Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Abstract Text:

J Beuth,H L Ko,Y Ohshima,F Schumacher-Perdreau,G Peters,G Pulverer,

Adhesion studies with cryotome sections of human kidney and lung respectively uroepithelial cells together with blocking experiments with competitive carbohydrates suggested that specific attachment of S. saprophyticus strain S 1 to host cells apparently is mediated by lectins. Accordingly, microbial lectin blocking with specific glycoconjugates or lectin dysfunction (after treatment of bacteria with subinhibitory concentrations of tunicamycin) significantly decreased staphylococcal adherence to epithelial cells. Chemiluminescence measurements of human polymorphonuclear leukocyte (PMN) function yielded results suggesting importance of lectin-receptor interaction in phagocytosis, too, since PMN activity was significantly decreased after staphylococcal lectin blocking or dysfunction.

Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Publishing Authors By Initials

J Beuth,HL Ko,Y Ohshima,F Schumacher-Perdreau,G Peters,G Pulverer,

For similar urogenital system: urinary tract research abstracts see: urogenital system: urinary tract research

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Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zentralblatt für Bakteriologie, Mikrobiologie, und

VOLUME: 270

Page Numbers: 22-7

Journal Abbreviation:

ISSN: 0176-6724

DAY: 12

MONTH: Nov

YEAR: 1988

Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Information

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LANGUAGE: eng

NlmUniqueID: 8403032

Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Keywords Mesh Terms:

KEYWORDS: Urinary Tract

MESH TERMS: microbiology

Chemical & Substance for Abstract: Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1. Information

Substance Name: Lectins

Registry Number: 0

Grant and Affiliation Information for Lectin-mediated cell-attachment and phagocytosis of Staphylococcus saprophyticus strain S1.

AFFILIATION: Hygiene-Institut, Universität Köln.

Country: GERMANY, WEST

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MEDLINETA: Zentralbl Bakteriol Mikrobiol

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