We tried to confirm the antioxidative capability of lecithin:cholesterol acyltransferase (LCAT) reported by Vohl et al. [Biochemistry (1999) 38, 5976-5981]. The enzyme solution protected LDL against oxidation. However, this protection was not due to LCAT enzyme, but to some unknown low-molecular-weight substance(s) in the solution; LCAT itself exerted little protective effect against LDL oxidation.
Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein. Publishing Authors By Initials
Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Journal of biochemistry
VOLUME: 131
Page Numbers: 17-9
Journal Abbreviation: J. Biochem.
ISSN: 0021-924X
DAY: 19
MONTH: Jan
YEAR: 2002
Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein. Information
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LANGUAGE: eng
NlmUniqueID: 376600
Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein. Keywords Mesh Terms:
KEYWORDS: Protein Denaturation
MESH TERMS: metabolism
Chemical & Substance for Abstract: Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein. Information
Grant and Affiliation Information for Lecithin: cholesterol acyltransferase is insufficient to prevent oxidative modification of low-density lipoprotein.
AFFILIATION: Laboratory of Nutrition, Graduate School of Agricultural Science, and Gene Research Center, Tohoku University, Tsutsumidori, Amamiya-machi, Aoba-ku, Sendai 981-8555, Japan.
Country: Japan
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MEDLINETA: J Biochem
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