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Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention.

Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Research Abstract Details 

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  • Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Abstract Text:

    p sampathP Sampath,l d rhinesL D Rhines,m j hollidayM J Holliday,h bremH Brem,d m longD M Long,

    Delayed facial nerve dysfunction after vestibular schwannoma surgery is a poorly understood phenomenon that has been reported to occur in 15 to 29% of patients undergoing microsurgery. It is a condition characterized by spontaneous deterioration of facial nerve function in a patient who has otherwise normal or near-normal facial function in the immediate postoperative period. This delayed paralysis is generally reported to occur in the first few days postsurgery, with the majority of patients eventually recovering their immediate postoperative facial function. However, infrequently, it can also occur more than 1 week after surgery (so-called late-onset facial nerve palsy). The authors reviewed facial nerve outcome in 611 patients who underwent microsurgery between 1973 and 1994. The facial nerve was anatomically preserved in 596 patients (97.5%), and 90% of patients had House-Brackmann[6] Grade 1 or 2 function 1 year after surgery. Late-onset facial dysfunction was seen in 13 patients (2.1%). All of these had significant deterioration in facial nerve function between 1 and 4 weeks postoperatively, and all showed improvement by 1 year. In this study, the focus on these patients who developed late-onset facial palsy. The incidence, treatment strategies, and outcomes will be discussed with emphasis on possible pathophysiological mechanisms that contribute to this relatively rare condition.

    Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Publishing Authors By Initials

    p sampathP Sampath,ld rhinesLD Rhines,mj hollidayMJ Holliday,h bremH Brem,dm longDM Long,

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    Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Neurosurgical focus

    VOLUME: 5

    Page Numbers: e6

    Journal Abbreviation:

    ISSN: 1092-0684

    DAY: 15

    MONTH: Sep

    YEAR: 1998

    Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Information

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    LANGUAGE: eng

    NlmUniqueID: 100896471

    Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention. Keywords Mesh Terms:

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    Grant and Affiliation Information for Late-onset facial nerve degeneration after vestibular schwannoma surgery: incidence, putative mechanisms, and prevention.

    AFFILIATION: Departments of Neurological Surgery and Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, Maryland.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Neurosurg Focus

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