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Large basophilic cells in the bone marrow in iron deficiency anemia.

Large basophilic cells in the bone marrow in iron deficiency anemia. Research Abstract Details 

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  • Large basophilic cells in the bone marrow in iron deficiency anemia. Abstract Text:

    n buyssensN Buyssens,m de weertM De Weert,n bourgeoisN Bourgeois,

    Many large cells with a strongly basophilic cytoplasm and large nuclei with a delicate chromatin pattern and large nucleoli were studied in 1 mu sections of core biopsies in 8 patients with iron deficiency anemia and in 5 patients with pernicious anemia. In 2 normal controls these cells were rare. Possible features of granulocytic differentiation were assessed with the Giemsa stain and with the naphtol-ASD-chloroacetate esterase reaction which is indicative of early granule formation: the large cells were constantly negative. In thin sections the morphological appearances of the large basophilic cells are rather similar in such different haematological disorders as pernicious anemia or iron deficiency anemia. A clear difference can be demonstrated by karyometry, which shows that the large basophilic cells in pernicious anemia are significantly larger than those in iron deficiency anemia or in the normal control.

    Large basophilic cells in the bone marrow in iron deficiency anemia. Publishing Authors By Initials

    n buyssensN Buyssens,m de weertM De Weert,n bourgeoisN Bourgeois,

    For similar investigative techniques: clinical laboratory techniques: cytological techniques: karyometry research abstracts see: investigative techniques: clinical laboratory techniques: cytological techniques: karyometry research

    PUBMED ID PMID:

    MEDLINE DATE:

    Large basophilic cells in the bone marrow in iron deficiency anemia. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Virchows Archiv. A, Pathological anatomy and histo

    VOLUME: 384

    Page Numbers: 357-62

    Journal Abbreviation:

    ISSN: 0340-1227

    DAY: 20

    MONTH: Oct

    YEAR: 1979

    Large basophilic cells in the bone marrow in iron deficiency anemia. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7505137

    Large basophilic cells in the bone marrow in iron deficiency anemia. Keywords Mesh Terms:

    KEYWORDS: Karyometry

    MESH TERMS: pathology

    Chemical & Substance for Abstract: Large basophilic cells in the bone marrow in iron deficiency anemia. Information

    Substance Name: Chromatin

    Registry Number: 0

    Grant and Affiliation Information for Large basophilic cells in the bone marrow in iron deficiency anemia.

    AFFILIATION:

    Country: GERMANY, WEST

    GERMANY, WEST Research PublicationGERMANY, WEST Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Virchows Arch A Pathol Anat Hi

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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