Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks.

Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. Research Abstract Details 

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Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. Abstract Text:

Leanna K Nosbisch,Aravinda M de Silva,

VlsE is a surface exposed lipoprotein of the Lyme disease spirochete, Borrelia burgdorferi. Spirochetes are able to generate many antigenic variants of VlsE by DNA recombination at the vlsE locus. Novel VlsE antigenic variants are readily observed in mice infected with B. burgdorferi. We followed a clonal population of spirochetes through a tick transmission cycle and report that unlike in vertebrates, the vlsE locus is stable in ticks.

Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. Publishing Authors By Initials

LK Nosbisch,AM de Silva,

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Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of medical entomology

VOLUME: 44

Page Numbers: 168-70

Journal Abbreviation: J. Med. Entomol.

ISSN: 0022-2585

DAY: 13

MONTH: Jan

YEAR: 2007

Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks. Information

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LANGUAGE: eng

NlmUniqueID: 375400

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Grant and Affiliation Information for Lack of detectable variation at Borrelia burgdorferi vlsE locus in ticks.

AFFILIATION: Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

Country: United States

AGENCY: United States NIAMS

GRANT: R01 AR047948

ACRONYM: AR

MEDLINETA: J Med Entomol

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