Kinetics of epidermal growth factor in saliva.

Kinetics of epidermal growth factor in saliva. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Kinetics of epidermal growth factor in saliva. Abstract Text:

M Ino,K Ushiro,C Ino,T Yamashita,T Kumazawa,

Human epidermal growth factor (hEGF) stimulates the growth and differentiation of various tissues. We measured EGF levels in saliva (n = 128), urine (n = 94), and serum (n = 99) with radioimmunoassay in order to study the kinetics of hEGF in saliva of normal subjects and patients with oral disease. Salivary EGF levels showed an apparent diurnal rhythm related to the taking of meals. Urinary and serum EGF levels showed no obvious diurnal rhythm. There was no significant correlation between salivary and urinary EGF levels, nor between salivary and serum EGF levels. Salivary EGF levels were significantly lower in the younger group (0-9 years old, 3.06 +/- 0.32 ng/ml, p < 0.05) than in the elder group (10-79 years old, 4.78 +/- 3.5 ng/ml), but did not correlate with age in the elder group. There was no significant difference between males and females between EGF levels in saliva, urine or serum. The relative proportion of EGF levels in submandibular gland saliva, parotid saliva, and whole saliva was 1:6:4. The positive rate of immunohistochemical EGF showed no significant differences between submandibular gland, parotid gland, sublingual gland or minor salivary gland. Salivary EGF levels were markedly low in patients with oral inflammations (stomatitis aphthosa, or peritonsillar abscess) or head and neck tumors (squamous cell carcinoma of the tongue, oral cavity, hypopharynx or larynx). These findings may be significant pathophysiologically. Low salivary EGF levels may reduce the capacity of oral mucosal defense mechanisms to fight against injury by physiochemical agents.

Kinetics of epidermal growth factor in saliva. Publishing Authors By Initials

M Ino,K Ushiro,C Ino,T Yamashita,T Kumazawa,

For similar stomatognathic diseases: mouth diseases: stomatitis research abstracts see: stomatognathic diseases: mouth diseases: stomatitis research

PUBMED ID PMID:

MEDLINE DATE:

Kinetics of epidermal growth factor in saliva. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 500

Page Numbers: 126-30

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1993

Kinetics of epidermal growth factor in saliva. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

Kinetics of epidermal growth factor in saliva. Keywords Mesh Terms:

KEYWORDS: Stomatitis

MESH TERMS: metabolism

Chemical & Substance for Abstract: Kinetics of epidermal growth factor in saliva. Information

Substance Name: Epidermal Growth Factor

Registry Number: 62229-50-9

Grant and Affiliation Information for Kinetics of epidermal growth factor in saliva.

AFFILIATION: Department of Otorhinolaryngology, Kansai Medical University, Osaka, Japan.

Country: SWEDEN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Kinetics of epidermal growth factor in saliva Related Publications

• A possible masking effect of tinnitus. Evaluation of CNV audiometry.
• Active opening function of the human eustachian tube: comparison between sonotubometry and pressure equilibration test.
• Approach to the diagnosis of sialadenosis using sialography.
• Autonomic nervous system in human palatine tonsil.
• Effects of acetazolamide on acid-base balance in the endolymphatic sac of the guinea pig.
• Effects of efferent neurotransmitters on intracellular Ca2+ concentration in vestibular hair cells of the guinea pig.
• Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.
• Enhanced parasympathetic nerve activities in experimentally-induced nasal hypersensitivity.
• Establishment of a cisplatin-resistant KB cell line and its characterization.
• Experimental and clinical evaluation of DNA ploidy with use of double staining of keratin/DNA by flow cytometer in head and neck tumor.
• Functional disturbances of the sympathetic nerve in experimentally-induced nasal hypersensitivity.
• Head and neck reconstruction with microvascular tissue transfer and its surgical indications: our experiences. A review.
• Histamine and acetylcholine regulation of sympathetic nerve activity in guinea-pig nasal mucosa.
• Histamine content and histamine H1 receptor in experimentally-induced nasal hypersensitivity.
• Kinetics of epidermal growth factor in saliva.
• Menière's disease and autoimmunity: clinical study and survey.
• Middle ear ventilation mechanism.
• Molecular phylogenetic and dating analyses using mitochondrial DNA sequences of eyelid geckos (Squamata: Eublepharidae).
• Norepinephrine content in guinea-pig nasal mucosa response to histamine and methacholine provocation.
• Otitis media with effusion and eustachian tube dysfunction in adults and children.
• Otitis media with effusion and tubal tonsil (video).
• Participation of autonomic nerve in tonsillar focal infection.
• Recent activities in otolaryngology -- head and neck surgery. Dedicated to Professor Tadami Kumazawa.
• Regulation of Cl- conductance in delayed shortening and shrinkage of outer hair cells.
• Subjective results of laser surgery for allergic rhinitis.
• Surgical anatomy for infralabyrinthine approach to the internal auditory canal.
• The tonsillar immune system: its response to exogenous antigens.
• The usefulness of partial parotidectomy for benign parotid gland tumors. A retrospective study of 306 cases.
• Thermal influence on intracellular calcium concentration in vestibular hair cells isolated from the guinea pig. A preliminary report.
• Thyroid follicle transplantation by percutaneous injection.