Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a benign and self-limited disease that mainly affects young women. Patients present with localized lymphadenopathy, fever, and leukopenia in up to half of the cases. KFD can occur in association with systemic lupus erythematosus. We present the case of a patient with KFD and systemic lupus erythematosus, as well as relapsing polychondritis. This patient had persistently low C4 complement levels, so she was evaluated for a genetic defect in complement production and was found to have two "null" C4 alleles. We believe that this may have contributed to the development of her diseases.
Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis): report of a case with other autoimmune manifestations. Publishing Authors By Initials
Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis): report of a case with other autoimmune manifestations. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Proceedings (Baylor University. Medical Center)
VOLUME: 20
Page Numbers: 149-51
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ISSN: 0899-8280
DAY: 13
MONTH: Apr
YEAR: 2007
Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis): report of a case with other autoimmune manifestations. Information
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LANGUAGE: eng
NlmUniqueID: 9302033
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AFFILIATION: Division of Rheumatology (Merriman), Division of Hematology/Medical Oncology (Stone), Department of Internal Medicine (Mahajan), Baylor University Medical Center, Dallas, Texas.
Country: United States
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MEDLINETA: Proc (Bayl Univ Med Cent)
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