Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis.

Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Research Abstract Details 

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Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Abstract Text:

Pei-Lin Wu,Yu-Lin Hsu,Tian-Shung Wu,K F Bastow,Kuo-Hsiung Lee,

[Structure: see text] Three new compounds, kalanchosides A-C (1-3), as well as five known compounds, were isolated from the aerial parts of Kalanchoe gracilis. The compound structures were determined by spectroscopic methods. All eight isolated compounds showed significant cytotoxic activity against a panel of human tumor cell lines, with potency reaching the nanomolar range. However, only bryophyllin B (8) inhibited HIV replication in H9 lymphocyte cells.

Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Publishing Authors By Initials

PL Wu,YL Hsu,TS Wu,KF Bastow,KH Lee,

For similar carbohydrates: glycosides: saponins research abstracts see: carbohydrates: glycosides: saponins research

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Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Organic letters

VOLUME: 8

Page Numbers: 5207-10

Journal Abbreviation: Org. Lett.

ISSN: 1523-7060

DAY: 9

MONTH: Nov

YEAR: 2006

Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Information

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LANGUAGE: eng

NlmUniqueID: 100890393

Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Keywords Mesh Terms:

KEYWORDS: Saponins

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Information

Substance Name: hellebrigenin-3-O-fucopyranoside

Registry Number: 0

Grant and Affiliation Information for Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis.

AFFILIATION: Department of Cosmetic Science, Chung Hwa College of Medical Technology, Tainan 717, Taiwan, Republic of China. wupl@mail.ncku.edu.tw

Country: United States

AGENCY: United States NCI

GRANT: CA17625

ACRONYM: CA

MEDLINETA: Org Lett

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