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Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1.

Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Research Abstract Details 

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  • Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Abstract Text:

    han wangHan Wang,eric myung-jae leeEric Myung-Jae Lee,steven m sperberSteven M Sperber,shuo linShuo Lin,marc ekkerMarc Ekker,qiaoming longQiaoming Long,

    We report the expression patterns of tsh1, a zebrafish homologue of the Drosophila homeotic gene teashirt. Expression of tsh1 is first detected at the 2-somite stage (10h post-fertilization, hpf) at the anterior end of the spinal cord. Expression expands toward the posterior spinal cord, and by the prim-5 stage (24 hpf) tsh1 transcripts are detected throughout spinal cord. Between the 14- and 25-somite stage (16-24 hpf), spinal cord expression shows a clear anterior boundary at the rostral margin of rhombomere 7. Around the prim-25 stage (36 hpf), while the spinal expression of tsh1 decreases, new expression is detected in the pectoral fin buds and dorsal forebrain. By the long-pec stage (48 hpf), spinal cord expression is undetectable, but strong expression is observed in the rhombencephalon, telencephalon, tectum opticum, midbrain-hindbrain boundary, in the first pharyngeal arch and in the eyes. This expression persists at least until the larval stages. Retinoic acid signaling influences tsh1 expression. Zebrafish tsh1 expression was induced in the anterior neural tube in embryos treated briefly with exogenous retinoic acid. Furthermore, tsh1 expression was down-regulated in the spinal cord in the zebrafish neckless mutant in which RA signaling is disrupted due to a missense mutation in the gene encoding retinaldehyde dehydrogenase type 2.

    Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Publishing Authors By Initials

    h wangH Wang,em leeEM Lee,sm sperberSM Sperber,s linS Lin,m ekkerM Ekker,q longQ Long,

    For similar proteins: fish proteins: zebrafish proteins research abstracts see: proteins: fish proteins: zebrafish proteins research

    PUBMED ID PMID:

    MEDLINE DATE:

    Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Gene expression patterns : GEP

    VOLUME: 7

    Page Numbers: 318-22

    Journal Abbreviation: Gene Expr. Patterns

    ISSN: 1567-133X

    DAY: 26

    MONTH: 08

    YEAR: 2006

    Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101167473

    Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Keywords Mesh Terms:

    KEYWORDS: Zebrafish Proteins

    MESH TERMS: genetics

    Chemical & Substance for Abstract: Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. Information

    Substance Name: Retinal Dehydrogenase

    Registry Number: EC 1.2.1.36

    Grant and Affiliation Information for Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1.

    AFFILIATION: Department of Zoology and Stephenson Research and Technology Center, University of Oklahoma, Norman, OK 73019, USA.

    Country: Netherlands

    Netherlands Research PublicationNetherlands Research Publication

    AGENCY: United States NCRR

    GRANT: 1P20RR17703-04

    ACRONYM: RR

    MEDLINETA: Gene Expr Patterns

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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