Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology.

Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Research Abstract Details 

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Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Abstract Text:

Noriaki Tomura,Osamu Watanabe,Koki Kato,Satoshi Takahashi,Jiro Watarai,Masato Sageshima,Michinori Yokomizo,

OBJECTIVE: MR imaging was prospectively correlated with pathologic findings to study whether MR imaging can differentiate viable from nonviable tumor tissue in the irradiated carcinoma of the tongue. SUBJECTS AND METHODS: MR examinations were performed after radiation therapy in 21 patients with carcinoma of the tongue. All patients underwent either a total glossectomy or hemiglossectomy after radiation therapy. Specimens were examined microscopically. Radiation changes were histologically graded into four groups (I, minimal cellular changes; II, presence of cellular changes and partial destruction of the tumor; III, only nonviable tumor cells; IV, no tumor cells). MR examinations included T2-weighted imaging, unenhanced T1-weighted imaging, dynamic contrast-enhanced imaging, and contrast-enhanced T1-weighted imaging. RESULTS: On unenhanced T1-weighted images, the lesion was hypointense, except for two patients with histologic grade III. On T2-weighted images, the lesion appeared hyperintense in 12 of 14 patients with viable tumor cells (grades I and II); however, the lesion was hypointense in four, and isointense in two of seven patients with nonviable tumor cells (grades III or IV). Contrast-enhanced T1-weighted images showed that the degree of contrast enhancement of the lesion was equal to or lower than that of a normal salivary gland in 18 of 21 patients. For the time of maximal enhancement of the lesion on dynamic imaging, there was no substantial difference between viable (grades I and II) and nonviable (grades III and IV) tumor tissue. CONCLUSION: The present study shows that T2-weighted imaging is feasible for differentiating viable from nonviable tumor tissue in irradiated carcinoma of the tongue.

Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Publishing Authors By Initials

N Tomura,O Watanabe,K Kato,S Takahashi,J Watarai,M Sageshima,M Yokomizo,

For similar neoplasms: neoplasms by site: head and neck neoplasms: mouth neoplasms: tongue neoplasms research abstracts see: neoplasms: neoplasms by site: head and neck neoplasms: mouth neoplasms: tongue neoplasms research

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Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 178

Page Numbers: 705-10

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Mar

YEAR: 2002

Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Keywords Mesh Terms:

KEYWORDS: Tongue Neoplasms

MESH TERMS: radiotherapy

Chemical & Substance for Abstract: Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology. Information

Substance Name: Gadolinium DTPA

Registry Number: 80529-93-7

Grant and Affiliation Information for Irradiated carcinoma of the tongue: correlation of MR imaging findings with pathology.

AFFILIATION: Department of Radiology, Akita University School of Medicine, 1-1-1, Hondo, Akita City, Akita, 010-8543, Japan.

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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