Iron and infection: the clinical evidence.

Iron and infection: the clinical evidence. Research Abstract Details 

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Iron and infection: the clinical evidence. Abstract Text:

Iron deficiency is prevalent in childhood in the developed and developing countries. Programs of presumptive therapy, mass supplementation and food fortification have been introduced in many countries. The unresolved debate over the interaction of iron and infection in the clinical setting prompts re-evaluation of these practices. Situations of iron overload are associated with increased susceptibility to certain infections, although the exact mechanisms may vary with the main pathology. Iron treatment has been associated with acute exacerbations of infection, in particular malaria. In most instances parenteral iron was used. In the neonate parenteral iron is associated with serious E. coli sepsis. In one country, with endemic malaria, parenteral iron was associated with increased rates of malaria and increased morbidity due to respiratory disease in infants. In contrast in non-malarious countries studies of oral iron supplementation have if anything shown a reduction in infectious morbidity. Methodological problems in the latter reports indicate the need for further controlled prospective studies with accurate morbidity recording if informed recommendations are to be made.

Iron and infection: the clinical evidence. Publishing Authors By Initials

For similar inorganic chemicals: elements: metals, heavy: iron research abstracts see: inorganic chemicals: elements: metals, heavy: iron research

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Iron and infection: the clinical evidence. Journal Published:

PUBLICATION TYPE: Review

Journal: Acta paediatrica Scandinavica. Supplement

VOLUME: 361

Page Numbers: 53-62

Journal Abbreviation:

ISSN: 0300-8843

DAY: 20

MONTH: 02

YEAR: 1989

Iron and infection: the clinical evidence. Information

Number of References: 98

LANGUAGE: eng

NlmUniqueID: 173166

Iron and infection: the clinical evidence. Keywords Mesh Terms:

KEYWORDS: Iron

MESH TERMS: physiology

Chemical & Substance for Abstract: Iron and infection: the clinical evidence. Information

Substance Name: Iron

Registry Number: 7439-89-6

Grant and Affiliation Information for Iron and infection: the clinical evidence.

AFFILIATION: Department of Paediatrics, Universiti Sains Malaysia, Kubang Kerian, Kelantan.

Country: SWEDEN

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MEDLINETA: Acta Paediatr Scand Suppl

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