Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch.

Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Research Abstract Details 

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Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Abstract Text:

C Epe,K Roesler,T Schnieder,M Stoye,

The aim of this investigation was to examine whether reactivated Ancylostoma caninum larvae can be eliminated by the administration of moxidectin to pregnant bitches. Four pregnant bitches infected experimentally with 20,000 third-stage larvae of A. caninum were treated subcutaneously with 1 mg moxidectin/kg body weight on day 55 of the pregnancy (5-8 days before parturition). Another four experimentally infected pregnant bitches served as controls. The single moxidectin treatment completely prevented lactogenic infections in the puppies. Neither intestinal stages nor somatic larvae could be found. The administration of moxidectin caused no local or systemic side-effects in the bitches. All 22 puppies of the treated bitches were born healthy and remained so during the whole trial period. Beginning during the third week after birth, all 20 puppies of the untreated bitches developed a severe microcytic, hypochromic anaemia and they revealed a total of 8649 intestinal stages of A. caninum after autopsy.

Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Publishing Authors By Initials

C Epe,K Roesler,T Schnieder,M Stoye,

For similar parasitic diseases: pregnancy complications, parasitic research abstracts see: parasitic diseases: pregnancy complications, parasitic research

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Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 46

Page Numbers: 361-7

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: Aug

YEAR: 1999

Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 331325

Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Keywords Mesh Terms:

KEYWORDS: Pregnancy Complications, Parasitic

MESH TERMS: veterinary

Chemical & Substance for Abstract: Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch. Information

Substance Name: milbemycin

Registry Number: 51570-36-6

Grant and Affiliation Information for Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of moxidectin to the bitch.

AFFILIATION: Institute of Parasitology, Hannover School of Veterinary Medicine, Germany.

Country: GERMANY

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MEDLINETA: Zentralbl Veterinarmed B

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