[Investigation of proximal femoral marrow with magnetic resonance imaging in recovered patients with severe acute respiratory syndrome]

[Investigation of proximal femoral marrow with magnetic resonance imaging in recovered patients with severe acute respiratory syndrome] Research Abstract Details 

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[Investigation of proximal femoral marrow with magnetic resonance imaging in recovered patients with severe acute respiratory syndrome] Abstract Text:

Jun Shen,Bi-ling Liang,Qing-si Zeng,Jian-yu Chen,Qing-yu Liu,Rong-chang Chen,Nan-shan Zhong,

OBJECTIVE: To determine the effect of corticosteroid treatment and severe acute respiratory syndrome (SARS) infection itself on the marrow conversion in the proximal femoral marrow in the recovered patients of health care workers with SARS. METHODS: The distribution of proximal femoral marrow on MR imaging of 148 health care workers with recovered SARS including 106 cases treated with varied dosage of steroids and 42 cases without steroid, and 97 age and sex matched health adults as controls were observed. The index of marrow conversion (signal intensity of the femoral neck and intertrochanteric area divided by signal intensity of the greater trochanter multiplied by 100%) was quantitatively measured and compared between SARS patients treated with steroid and without steroid and the normal control group. RESULTS: In 106 cases treated with steroid of the 148 health care workers, femoral head osteonecrosis was found in 4 cases, bilateral femoral marrow edema in 2 cases, femoral marrow infarction in 1 case. The index of marrow conversion in the normal controls, in SARS patients treated without and with steroids was (79.4 +/- 6.8)%, (86.9 +/- 7.4)%, (88.6 +/- 5.9)%, respectively. There was significantly statistical difference between groups (P < 0.05). CONCLUSION: In addition to fat conversion in the proximal femoral marrow due to steroid treatment, the infection of SARS itself may promote an excessively conversion of the red marrow to yellow marrow of the femoral neck in SARS patients.

[Investigation of proximal femoral marrow with magnetic resonance imaging in recovered patients with severe acute respiratory syndrome] Publishing Authors By Initials

J Shen,BL Liang,QS Zeng,JY Chen,QY Liu,RC Chen,NS Zhong,

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[Investigation of proximal femoral marrow with magnetic resonance imaging in recovered patients with severe acute respiratory syndrome] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe h

VOLUME: 29

Page Numbers: 189-93

Journal Abbreviation: Zhonghua Jie He He Hu Xi Za Zh

ISSN: 1001-0939

DAY: 8

MONTH: Mar

YEAR: 2006

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LANGUAGE: chi

NlmUniqueID: 8712226

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AFFILIATION: Department of Radiology, Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510120, China.

Country: China

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MEDLINETA: Zhonghua Jie He He Hu Xi Za Zh

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