Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery.

Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Research Abstract Details 

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Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Abstract Text:

Xue-Min Li,Lizhong Hu,Jinping Hu,Wei Wang,Xue-Min Li,Lizhong Hu,Jinping Hu,Wei Wang,

PURPOSE: To study dry eye and analyze pathogenic factors in patients after cataract surgery. METHODS: A total of 37 patients (50 eyes) were studied by using a 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ25) and Ocular Surface Disease Index (OSDI) 3 days before and 1 week, 1 month, and 3 months after cataract surgery. Slit-lamp microscope examination, cornea and conjunctiva fluorescein staining, tear breakup time (BUT), Schirmer test I (STI), and impression cytology (IC) were carried out at the same time. Cytologic specimens for IC were obtained from the upper lid-covered region, explosive region, and lower lid-covered region of the globe conjunctiva. The average density of goblet cells on these 3 regions was measured, and the pathogenic factors of dry eye after cataract surgery were analyzed. RESULTS: After cataract surgery, the incidence of dry eye increased dramatically; NEI-VFQ25 and OSDI indicated that most patients developed this symptom after surgery. The lacrimal river line became narrow, and BUT and STI decreased in patients after cataract surgery. IC suggested the presence of serious squamous metaplasia in the epithelial layer of the globe conjunctiva, especially the lower lid region. CONCLUSIONS: Dry eye can develop or deteriorate after cataract surgery if not treated in time. Misuse of eyedrops is one of the major pathogenic factors that causes dry eye after cataract surgery. Eyedrops should be carefully administered before and after cataract surgery to avoid or reduce the occurrence of dry eye postoperatively.

Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Publishing Authors By Initials

XM Li,L Hu,J Hu,W Wang,XM Li,L Hu,J Hu,W Wang,

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Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cornea

VOLUME: 26

Page Numbers: S16-20

Journal Abbreviation: Cornea

ISSN: 0277-3740

DAY: 20

MONTH: Oct

YEAR: 2007

Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Information

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LANGUAGE: eng

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AFFILIATION: Beijing University Ophthalmic Center, Beijing University Third Hospital, Beijing 100 083, China.

Country: United States

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MEDLINETA: Cornea

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