Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors.

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Abstract Text:

Satoshi Hirasawa,Yoshito Tsushima,Hiroyuki Takei,Hiromi Hirasawa,Ayako Taketomi-Takahashi,Akie Takano,Noboru Oriuchi,Keigo Endo,

RATIONALE AND OBJECTIVES: We sought to determine the relationship between tumor blood flow and glucose uptake in head and neck tumors using perfusion computed tomography (PCT) and fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET). MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained for this study. Sixteen patients (mean age, 67 years; age range, 36-89 years) who had known or suspected head and neck tumors (15 malignant tumors and one schwannoma) underwent PCT and FDG PET examinations. Tumor area was measured on conventional CT images. The PCT data were postprocessed using maximum slope method analysis, and standardized uptake value (SUV) was measured on FDG PET. RESULTS: Mean arterial perfusion of the tumors was 61.56 mL/min/100 mL (range 22.17-102.7 mL/min/100 mL), and mean FDG SUV was 7.48 (range 2.74-17.1). A significant negative correlation between arterial perfusion and FDG SUV was found for malignant tumors (r = -0.538, P = .04, n = 15). CONCLUSION: There was an inverse relationship between arterial perfusion and glucose uptake of head and neck malignant tumors, suggesting that the malignant tumors may depend on anaerobic glycolysis.

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Publishing Authors By Initials

S Hirasawa,Y Tsushima,H Takei,H Hirasawa,A Taketomi-Takahashi,A Takano,N Oriuchi,K Endo,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Academic radiology

VOLUME: 14

Page Numbers: 312-8

Journal Abbreviation:

ISSN: 1076-6332

DAY: 19

MONTH: Mar

YEAR: 2007

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9440159

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors.

AFFILIATION: Department of Diagnostic and Interventional Radiology, Gunma Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acad Radiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors Related Publications

• A Possible treatment strategy and clinical factors to estimate the treatment response in Bebesia gibsoni infection.
• Antiinflammatory mediator lipoxin A4 and its receptor in synovitis of patients with rheumatoid arthritis.
• Comparative characterization study of microporous carbons by HRTEM image analysis and gas adsorption.
• Cystic teratoma of the diaphragm which mimicked soft tissue lipoma.
• Design of new phosphonic acid monomers for dental adhesives--synthesis of (meth) acryloxyalkyl 3-phosphonopropionates and evaluation of their adhesion-promoting functions.
• Early diagnosis of recurrent hepatocellular carcinoma with 18F-FDG PET after radiofrequency ablation therapy.
• Effects of intrafractional motion on water equivalent pathlength in respiratory-gated heavy charged particle beam radiotherapy.
• Electron paramagnetic resonance and optical absorption spectral studies on chalcocite.
• Establishment of novel human dedifferentiated chondrosarcoma cell line with osteoblastic differentiation.
• Four cases of chemical burns thought to be caused by exposure to chromic acid mist.
• Impact of anomalous origin of the ophthalmic artery from the middle meningeal artery on selection of surgical approach to skull base meningioma.
• In situ small-angle neutron scattering and rheological measurements of shear-induced gelation.
• Indomethacin solubilization induced shape transition in C(n)E(7) (n=14,16) nonionic micelles.
• Intermolecular potential energy surface of Ar-NO.
• Inverse correlation between tumor perfusion and glucose uptake in human head and neck tumors.
• Laser induced fluorescence spectroscopy of the C(3)N radical.
• Malignant transformation of clival chordoma after gamma knife surgery - case report - .
• Molecular aggregates of partially fluorinated quaternary ammonium salt gemini surfactants.
• Multi-purpose bonding performance of newly synthesized phosphonic acid monomers.
• Multiple meningiomas consisting of fibrous meningioma and anaplastic meningioma.
• Oral bacterial lipopolysaccharide acts in mice to promote sensitisation to ovalbumin and to augment anaphylaxis via platelets.
• Ossifying fibromyxoid tumor of soft parts with clonal chromosomal aberrations.
• Preliminary study: color map of hepatocellular carcinoma using dynamic contrast-enhanced 256-detector row CT.
• Stem cells and plasticity of skeletal muscle cell differentiation: potential application to cell therapy for degenerative muscular diseases.
• The alpha/beta Interfaces of alpha1beta1, alpha3beta3, and F1: Domain Motions and Elastic Energy Stored during gamma Rotation.
• Three-dimensional, Computer-tomographic Analysis of Membrane Proteins (TrkA, caveolin, clathrin) in PC12 Cells.
• Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells.
• [Clinical use of nuclear medicine in the management of thyroid disease]
• [Epidemiology of dyspepsia and its therapeutic approach. Clinical practice starts with good relationship with patients]
• cDNA cloning and functional expression of a human monocyte chemoattractant protein 1 receptor.