Intravenous immunoglobulin: a review.

Intravenous immunoglobulin: a review. Research Abstract Details 

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Intravenous immunoglobulin: a review. Abstract Text:

Intramuscular immunoglobulin products developed for the prophylaxis of viral diseases and used in replacement therapy in immunodeficiency diseases have been superseded by products suitable for intravenous administration. Modified and intact immunoglobulin preparations are available for therapeutic use; only the intact products express full Fc-mediated function and the biological half-life of IgG (3-4 weeks). While adverse reactions to intravenous immunoglobulin (IVIG) do occur, they are infrequent. Rare clusters of non-A, non-B hepatitis after the use of some lots of IVIG have been reported. Transmission of HIV has never been documented. The administration of IVIG in replacement therapy in primary immunodeficiency syndromes and in secondary immunodeficiencies, as well as for the prevention and treatment of infectious diseases, is discussed, and reports of the use of IVIG for immune modulation in autoimmune and immune-complex disease are summarized.

Intravenous immunoglobulin: a review. Publishing Authors By Initials

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Intravenous immunoglobulin: a review. Journal Published:

PUBLICATION TYPE: Review

Journal: Immunodeficiency reviews

VOLUME: 1 Suppl

Page Numbers: 1-42

Journal Abbreviation: Immunodefic Rev

ISSN: 0893-5300

DAY: 6

MONTH: 03

YEAR: 1989

Intravenous immunoglobulin: a review. Information

Number of References: 364

LANGUAGE: eng

NlmUniqueID: 9001383

Intravenous immunoglobulin: a review. Keywords Mesh Terms:

KEYWORDS: Safety

MESH TERMS: therapy

Chemical & Substance for Abstract: Intravenous immunoglobulin: a review. Information

Substance Name: Immunoglobulins

Registry Number: 0

Grant and Affiliation Information for Intravenous immunoglobulin: a review.

AFFILIATION: Institute of Immunology, University of Vienna, Austria.

Country: ENGLAND

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MEDLINETA: Immunodefic Rev

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