Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli.

Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Research Abstract Details 

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Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Abstract Text:

Z Wiesenfeld-Hallin,M J Villar,T Hökfelt,

The neuropeptide galanin (GAL) was injected intrathecally (i.t.) in decerebrate, spinalized, unanesthetized rats and its effect on the nocifensive flexor reflex was examined. The reflex, which was evoked by intense mechanical or thermal stimulation of the foot, was recorded from the ipsilateral hamstring muscles. I.t. GAL increased reflex excitability significantly more to thermal than to mechanical stimuli. It is suggested that GAL, which is present in sensory fibers that innervate the skin, is released by the central terminals of cutaneous afferents that are much more sensitive to thermal than to mechanical stimuli.

Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Publishing Authors By Initials

Z Wiesenfeld-Hallin,MJ Villar,T Hökfelt,

For similar nervous system: peripheral nervous system: nerve endings: receptors, sensory: thermoreceptors research abstracts see: nervous system: peripheral nervous system: nerve endings: receptors, sensory: thermoreceptors research

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Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 71

Page Numbers: 663-6

Journal Abbreviation:

ISSN: 0014-4819

DAY: 15

MONTH: 02

YEAR: 1988

Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Information

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LANGUAGE: eng

NlmUniqueID: 43312

Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Keywords Mesh Terms:

KEYWORDS: Thermoreceptors

MESH TERMS: physiology

Chemical & Substance for Abstract: Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Information

Substance Name: Galanin

Registry Number: 88813-36-9

Grant and Affiliation Information for Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli.

AFFILIATION: Department of Clinical Neurophysiology and Physiology, Huddinge University Hospital, Sweden.

Country: GERMANY, WEST

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MEDLINETA: Exp Brain Res

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