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Intracranial artery calcification: a newly identified risk factor of ischemic stroke.

Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Research Abstract Details 

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  • Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Abstract Text:

    xiang-yan chenXiang-yan Chen,wynnie wai man lamWynnie Wai Man Lam,ho keung ngHo Keung Ng,yu-hua fanYu-hua Fan,ka sing wongKa Sing Wong,

    BACKGROUND AND PURPOSE: Calcification in cerebral arteries is understudied, although frequently observed on computed tomography of the brain (CT brain). We aimed to assess the incidence of intracranial artery calcification in ischemic stroke patients and to evaluate its correlation with ischemic stroke. METHODS: Our study included ischemic stroke patients and age-gender-matched nonischemic stroke patients referred for CT brain. RESULTS: One hundred and seventy-five ischemic stroke patients and 182 controls were enrolled. The highest prevalence of calcification was seen in intracranial internal carotid artery (IICA) (80.4%), and less commonly in the vertebral artery (35.6%). There was a higher prevalence of intracranial artery calcification in ischemic stroke patients than controls (92.6% vs. 76.4%, P < .001). Hypertension (OR = 2.056, 95% CI: 1.129 approximately 3.745), diabetes (OR = 2.483, 95% CI: 1.233 approximately 5.001), smoking (OR = 2.844, 95% CI: 1.542 approximately 5.243), intracranial artery calcification (OR = 3.172, 95% CI: 1.252 approximately 8.036), hyperlipidemia (OR = 6.714, 95% CI: 3.302 approximately 13.650), and atrial fibrillation (OR = 7.941, 95% CI: 2.790 approximately 22.599) were found to be independently associated with ischemic stroke. CONCLUSIONS: We demonstrated a higher incidence of intracranial artery calcification in ischemic stroke patients. Besides traditional risk factors, intracranial artery calcification was found to be an independent risk factor of ischemic stroke.

    Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Publishing Authors By Initials

    xy chenXY Chen,ww lamWW Lam,hk ngHK Ng,yh fanYH Fan,ks wongKS Wong,

    For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

    PUBMED ID PMID:

    MEDLINE DATE:

    Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of neuroimaging : official journal of the

    VOLUME: 17

    Page Numbers: 300-3

    Journal Abbreviation:

    ISSN: 1051-2284

    DAY: 20

    MONTH: Oct

    YEAR: 2007

    Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9102705

    Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Keywords Mesh Terms:

    KEYWORDS: Tomography, X-Ray Computed

    MESH TERMS: radiography

    Chemical & Substance for Abstract: Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Information

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    Grant and Affiliation Information for Intracranial artery calcification: a newly identified risk factor of ischemic stroke.

    AFFILIATION: Department of Anatomical & Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: J Neuroimaging

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