Intracellular pH sensors: design principles and functional significance.

Intracellular pH sensors: design principles and functional significance. Research Abstract Details 

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Intracellular pH sensors: design principles and functional significance. Abstract Text:

Jyoti Srivastava,Diane L Barber,Matthew P Jacobson,

Changes in intracellular pH regulate many cell behaviors, including proliferation, migration, and transformation. However, our understanding of how physiological changes in pH affect protein conformations and macromolecular assemblies is limited. We present design principles, current modeling predictions, and examples of pH sensors or proteins that have activities or ligand-binding affinities that are regulated by changes in intracellular pH.

Intracellular pH sensors: design principles and functional significance. Publishing Authors By Initials

J Srivastava,DL Barber,MP Jacobson,

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: structure-activity relationship research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: structure-activity relationship research

PUBMED ID PMID:

MEDLINE DATE:

Intracellular pH sensors: design principles and functional significance. Journal Published:

PUBLICATION TYPE: Review

Journal: Physiology (Bethesda, Md.)

VOLUME: 22

Page Numbers: 30-9

Journal Abbreviation:

ISSN: 1548-9213

DAY: 3

MONTH: Feb

YEAR: 2007

Intracellular pH sensors: design principles and functional significance. Information

Number of References: 123

LANGUAGE: eng

NlmUniqueID: 101208185

Intracellular pH sensors: design principles and functional significance. Keywords Mesh Terms:

KEYWORDS: Structure-Activity Relationship

MESH TERMS: physiology

Chemical & Substance for Abstract: Intracellular pH sensors: design principles and functional significance. Information

Substance Name: Receptors, Cell Surface

Registry Number: 0

Grant and Affiliation Information for Intracellular pH sensors: design principles and functional significance.

AFFILIATION: Department of Cell and Tissue Biology, Unicversity of California-San Francisco, San Francisco, CA, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM 58642

ACRONYM: GM

MEDLINETA: Physiology (Bethesda)

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