Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging.

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Abstract Text:

A Ishii,Y Korogi,T Hirai,R Nishimura,R Murakami,I Ikushima,K Kawanaka,M Shinohara,Y Yamashita,A Ishii,Y Korogi,T Hirai,R Nishimura,R Murakami,I Ikushima,K Kawanaka,M Shinohara,Y Yamashita,

BACKGROUND: Although intraarterial chemotherapy has been used to treat head and neck cancers, some cases have shown poor response. If we can predict the response to this therapy on MRI, individual treatment plans may be altered to the most appropriate form of treatment. PURPOSE: To evaluate whether MRI can predict the histological response to preoperative chemoirradiation in patients with cancer of the mouth. MATERIAL AND METHODS: This study comprised of 29 consecutive patients with 30 oral cancers. All patients underwent tumor resection after intraarterial infusion chemotherapy and conformal radiotherapy. We compared the margin of the tumor, the presence of bone invasion, tumor area, and volume on pre- and post-treatment MRI with histological responses. RESULTS: Eighteen lesions showed an excellent response, nine exhibited a good response, and three a poor response. Only the tumor area on pretreatment T1-weighted images and the tumor area and volume on pretreatment enhanced T1-weighted images were significantly correlated with the histological response (P = 0.039, 0.008, and 0.016, respectively); smaller cancers showed better responses. The other factors were not significantly correlated with the histological responses. CONCLUSION: MRI parameters, excluding initial tumor area and volume, were not predictive of the histological response of oral tumors to preoperative treatment.

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Publishing Authors By Initials

A Ishii,Y Korogi,T Hirai,R Nishimura,R Murakami,I Ikushima,K Kawanaka,M Shinohara,Y Yamashita,A Ishii,Y Korogi,T Hirai,R Nishimura,R Murakami,I Ikushima,K Kawanaka,M Shinohara,Y Yamashita,

For similar therapeutics: radiotherapy: radiotherapy, computer-assisted: radiotherapy, conformal research abstracts see: therapeutics: radiotherapy: radiotherapy, computer-assisted: radiotherapy, conformal research

PUBMED ID PMID:

MEDLINE DATE:

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta radiologica (Stockholm, Sweden : 1987)

VOLUME: 48

Page Numbers: 900-6

Journal Abbreviation:

ISSN: 1600-0455

DAY: 23

MONTH: Oct

YEAR: 2007

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8706123

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Keywords Mesh Terms:

KEYWORDS: Radiotherapy, Conformal

MESH TERMS: therapy

Chemical & Substance for Abstract: Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging. Information

Substance Name: Cisplatin

Registry Number: 15663-27-1

Grant and Affiliation Information for Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging.

AFFILIATION: Department of Diagnostic Radiology, Radiation Oncology, and Oral and Maxillofacial Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Country: Sweden

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Radiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging Related Publications

• Attitudes of commercial motor vehicle drivers towards safety belts.
• Autologous amnion graft for repair of myelomeningocele: technical note and clinical implication.
• Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present.
• Chromosome elimination in the interspecific hybrid medaka between Oryzias latipes and O. hubbsi.
• Differentiation of arterial, venous, and lymphatic endothelial cells from vascular progenitors.
• Direct observation of the ground-spin alignment of Fe(II)-Fe(III) single-chain magnet by muon-spin relaxation.
• Effects of changing the initial horizontal location of the center of mass on the anticipatory postural adjustments and task performance associated with step initiation.
• FGF23 is a hormone-regulating phosphate metabolism--unique biological characteristics of FGF23.
• Facial nerve paralysis: a complication of distraction osteogenesis of the mandibular ramus in the treatment of temporomandibular joint ankylosis.
• Guest editorial.
• Hyaluronan production regulation from porcine hyalocyte cell line by cytokines.
• Intraarterial infusion chemotherapy and conformal radiotherapy for cancer of the mouth: prediction of the histological response to therapy with magnetic resonance imaging.
• Mass spectrometric analysis of oxygenations in aromatization of androst-4-ene-3,6,17-trione, a suicide substrate of aromatase, by placental microsomes. Isotope effect and stereochemistry.
• Mechanisms of solute and fluid removal in hemodiafiltration.
• Molecular basis of thromboembolism in association with atrial fibrillation.
• Nuclear factor-kB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer.
• Obstructive hydrocephalus associated with arachnoid cyst in the elderly.
• Pistil and stamen of lily flowers bend upward by light.
• Prediction of aortic peak enhancement in monophasic contrast injection protocols at multidetector CT: phantom and patient studies.
• Prognostic significance of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 expression in breast cancer.
• Repulsion of cerebellar granule neurons by chondroitin sulfate proteoglycans is mediated by MAPK pathway.
• Results of a phase I clinical study using dendritic cell vaccinations for thyroid cancer.
• Role of cation-pi interactions in the photodimerization of trans-4-styrylpyridines.
• Role of heat shock protein 70 in induction of stress fiber formation in rat arterial endothelial cells in response to stretch stress.
• Spontaneous chronic head and spinal subdural haematoma.
• Survivors of violence-related facial injury: psychiatric needs and barriers to mental health care.
• The usefulness of diffusion-weighted imaging (DWI) for the detection of gastric cancer.
• Traumatic subdural hygroma: five cases with changed density and spontaneous resolution.
• Volatile allelopathy in velvet bean (Mucuna pruriens [correction ofpruiens] L.) and gravity.
• [Response of amphibians to the parabolic aircraft flight]