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Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves.

Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves. Research Abstract Details 

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  • Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves. Abstract Text:

    k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,

    We assessed the interaction of GH gene polymorphisms (AA, AB and BB genotypes) with body weight and measures of endocrine function in Japanese black calves at 10 months of age. The average body weight for the BB genotype (281+/-5kg) was significantly lower (P=0.0017, ANOVA) than those for the AA (324+/-9kg) and AB (317+/-7kg) genotypes. Plasma concentrations of insulin and IGF-I were greater for the AA genotype than for the AB genotype, and AB and BB genotypes, respectively. There were significant differences in the triglyceride and cholesterol concentrations among the GH genotypes. The area under the basal GH concentration was significantly greater (P=0.0314) for the AA genotype than for the two other genotypes. The incremental area over the basal GH concentrations in response to intravenous GHRH injection (0.4mug/kgBW) was significantly smaller (P=0.0005) for the BB genotype than for the two other genotypes. In addition, linear regression analysis between GH incremental area induced by GHRH and body weight demonstrated that there was a positive linear correlation (r=0.6496, P<0.002) for incremental areas less than 600ngmin/ml, but a negative correlation (r=0.6473, P<0.05) for incremental areas over 600ngmin/ml. These findings indicate that the GH genotypes of the animals could be associated with difference in the GH response in Japanese black cattle at 10 months of age. We also observed a relationship between genotype and animal performances, but other studies on more animals in different conditions must be realized to make a definite conclusion.

    Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves. Publishing Authors By Initials

    k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,k katohK Katoh,s kounoS Kouno,a okazakiA Okazaki,k suzukiK Suzuki,y obaraY Obara,

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    Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Domestic animal endocrinology

    VOLUME: 34

    Page Numbers: 25-30

    Journal Abbreviation: Domest. Anim. Endocrinol.

    ISSN: 0739-7240

    DAY: 13

    MONTH: 11

    YEAR: 2006

    Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves. Information

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    LANGUAGE: eng

    NlmUniqueID: 8505191

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    Grant and Affiliation Information for Interaction of GH polymorphism with body weight and endocrine functions in Japanese black calves.

    AFFILIATION: Department of Animal Physiology, Graduate School of Agricultural Science, Tohoku University, Aoba-ku, Sendai 981-8555, Japan.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Domest Anim Endocrinol

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