Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials.

Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials. Research Abstract Details 

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Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials. Abstract Text:

Rohit Varma,Lie-Ju Hwang,John W Grunden,Gerald W Bean,

PURPOSE: To evaluate whether inter-visit intraocular pressure (IOP) range, which reflects extreme and potentially damaging IOP fluctuations, provides additional information on IOP control compared to mean IOP. DESIGN: Post hoc analysis of Xalatan/Lumigan/Travatan study data, a masked-evaluator, randomized, parallel-group comparison of 12-week efficacy of latanoprost, bimatoprost, and travoprost in open-angle glaucoma/ocular hypertension patients. METHODS: Pretreatment inter-visit IOP range defined as highest IOP minus lowest IOP at screening, safety check, and baseline (six measurements); posttreatment inter-visit IOP range defined as highest IOP minus lowest IOP at weeks two, six, and 12 or early termination (nine measurements). Ranges dichotomized as "high" (>6 mm Hg) vs "low" (

Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials. Publishing Authors By Initials

R Varma,LJ Hwang,JW Grunden,GW Bean,

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Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: American journal of ophthalmology

VOLUME: 145

Page Numbers: 336-42

Journal Abbreviation: Am. J. Ophthalmol.

ISSN: 0002-9394

DAY: 28

MONTH: Feb

YEAR: 2008

Inter-visit Intraocular Pressure Range: An Alternative Parameter for Assessing Intraocular Pressure Control in Clinical Trials. Information

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LANGUAGE: eng

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AFFILIATION: Keck School of Medicine, University of Southern California, Los Angeles, California.

Country: United States

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MEDLINETA: Am J Ophthalmol

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