Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging.

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Abstract Text:

Tuhin K Sinha,Sheerin Khatib-Shahidi,Thomas E Yankeelov,Khubaib Mapara,Moneeb Ehtesham,D Shannon Cornett,Benoit M Dawant,Richard M Caprioli,John C Gore,Tuhin K Sinha,Sheerin Khatib-Shahidi,Thomas E Yankeelov,Khubaib Mapara,Moneeb Ehtesham,D Shannon Cornett,Benoit M Dawant,Richard M Caprioli,John C Gore,Tuhin K Sinha,Sheerin Khatib-Shahidi,Thomas E Yankeelov,Khubaib Mapara,Moneeb Ehtesham,D Shannon Cornett,Benoit M Dawant,Richard M Caprioli,John C Gore,

We have developed a method for integrating three dimensional-volume reconstructions of spatially resolved matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) ion images of whole mouse heads with high-resolution images from other modalities in an animal-specific manner. This approach enabled us to analyze proteomic profiles from MALDI IMS data with corresponding in vivo data provided by magnetic resonance imaging.

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Publishing Authors By Initials

TK Sinha,S Khatib-Shahidi,TE Yankeelov,K Mapara,M Ehtesham,DS Cornett,BM Dawant,RM Caprioli,JC Gore,TK Sinha,S Khatib-Shahidi,TE Yankeelov,K Mapara,M Ehtesham,DS Cornett,BM Dawant,RM Caprioli,JC Gore,TK Sinha,S Khatib-Shahidi,TE Yankeelov,K Mapara,M Ehtesham,DS Cornett,BM Dawant,RM Caprioli,JC Gore,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nature methods

VOLUME: 5

Page Numbers: 57-9

Journal Abbreviation: Nat. Methods

ISSN: 1548-7105

DAY: 16

MONTH: 12

YEAR: 2007

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101215604

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging.

AFFILIATION: Department of Radiology and Radiological Sciences, Vanderbilt University, 1161 21st Avenue South, Nashville, Tennessee 37232, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Nat Methods

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging Related Publications

• A Phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum-based regimens.
• A practical guide to robust detection of GABA in human brain by J-difference spectroscopy at 3 T using a standard volume coil.
• Adverse childhood experiences and mental health in young adults: a longitudinal survey.
• Amphibian emergency medicine.
• An Arabidopsis haplotype map takes root.
• Assessing functional connectivity in the human brain by fMRI.
• Assessing signal enhancement in distant dipolar field-based sequences.
• Calculation of RF Peak Power for 2D Arbitrary Shape Excitation in MRI.
• Comment on "Assessing functional connectivity in the human brain by fMRI".
• Comparison of a reference region model with direct measurement of an AIF in the analysis of DCE-MRI data.
• Detection and isolation of Japanese encephalitis virus from blood clots collected during the acute phase of infection.
• Development of 2dTCA for the detection of irregular, transient bold activity.
• Development of left occipitotemporal systems for skilled reading in children after a phonologically- based intervention.
• Effects of hypoglycemia on human brain activation measured with fMRI.
• Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.
• Hypoglycemia reduces the blood-oxygenation level dependent signal in primary auditory and visual cortex: a functional magnetic resonance imaging study.
• Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging.
• Integration of quantitative DCE-MRI and ADC mapping to monitor treatment response in human breast cancer: initial results.
• Long-term trends in the use of coronary reperfusion strategies in acute myocardial infarction: a community-wide perspective.
• Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography.
• Novel localization of NMDA receptors within neuroendocrine gonadotropin-releasing hormone terminals.
• Numerical study of water diffusion in biological tissues using an improved finite difference method.
• Optimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry.
• Quantitative magnetization transfer imaging via selective inversion recovery with short repetition times.
• Randomized adjuvant therapy trials in melanoma: surgical and systemic.
• Repeatability of a reference region model for analysis of murine DCE-MRI data at 7T.
• Serum glucose levels and hospital outcomes in patients with acute myocardial infarction without prior diabetes: a community-wide perspective.
• The effects of prenatal PCBs on adult female paced mating reproductive behaviors in rats.
• Tracking the migration of dendritic cells by in vivo optical imaging.
• Why endocrinologists need to take ownership of endocrine disruption.