Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions.

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Research Abstract Details 

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Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Abstract Text:

T J Bussey,R Dias,E S Redhead,J M Pearce,J L Muir,J P Aggleton,

It has been proposed that the hippocampal formation is necessary for the acquisition of tasks that require the use of configural representations for their solution, including spatial learning and negative patterning. Tests of this influential view have, however, yielded conflicting results. For example fornix or hippocampal lesions, which reliably impair spatial learning, do not reliably impair negative patterning. A problem in interpreting these results has been the lack of controls for factors such as over-responding, excitatory effects of reward, and the possibility of non-configural solutions. At the same time, other studies have pointed to a role in configural learning for parahippocampal regions such as the perirhinal cortex. The present experiments controlled for the above factors and revealed that neither lesions of the fornix nor of the perirhinal/postrhinal cortex in the rat had any effect on negative patterning, although subsequent tests of object and spatial memory demonstrated the functional efficacy of the lesions.

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Publishing Authors By Initials

TJ Bussey,R Dias,ES Redhead,JM Pearce,JL Muir,JP Aggleton,

For similar psychological phenomena and processes: mental processes: perception: space perception research abstracts see: psychological phenomena and processes: mental processes: perception: space perception research

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Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 134

Page Numbers: 506-19

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ISSN: 0014-4819

DAY: 15

MONTH: Oct

YEAR: 2000

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Information

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LANGUAGE: eng

NlmUniqueID: 43312

Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions. Keywords Mesh Terms:

KEYWORDS: Space Perception

MESH TERMS: physiology

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Grant and Affiliation Information for Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions.

AFFILIATION: Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA. bussey@ln.nimh.nih.gov

Country: GERMANY

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MEDLINETA: Exp Brain Res

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