Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis.

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Abstract Text:

To elucidate factors involved in the oral-aboral axis specification, several observations and experiments were undertaken using the sand dollar Scaphechinus mirabilis. Unlike in Strongylcentrotus purpuratus, localization of mitochondria was not detected in unfertilized eggs. After fertilization, however, the bulk of mitochondria became localized to the opposite side of sperm entry. The first cleavage divided this mitochondrial cluster into daughter blastomeres. On the other hand, a second cleavage produced daughter blastomeres containing quite different amounts of mitochondria. To know whether such mitochondrial localization affects the oral-aboral axis specification, 4-cell-stage embryos were separated along the second cleavage plane. Although both half embryos developed into morphologically normal plutei, some differences, such as the number of pigment cells, were noticed between the siblings. In contrast, cell tracing revealed that the first cleavage separated the oral from the aboral part in most cases, indicating that the unequal distribution of mitochondria is not critical for the oral-aboral axis specification. Further, stained and non-stained half embryo fragments were combined. Such combined embryos developed into normal plutei with a single oral-aboral axis. The plane dividing labeled and non-labeled parts were incident, oblique or perpendicular to the median plane of the combined embryo, and the appearance frequencies of those labeling patterns were similar to those obtained by cell tracing in intact embryos. Interestingly, the half fragments derived from embryos inseminated earlier showed a tendency to form the oral part. These suggest that several factors as well as the localized cytoplasmic components would be involved in the specification process of oral-aboral axis.

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Development, growth & differentiation

VOLUME: 50

Page Numbers: 675-87

Journal Abbreviation: Dev. Growth Differ.

ISSN: 1440-169X

DAY: 1

MONTH: Oct

YEAR: 2008

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 356504

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis.

AFFILIATION: Department of Biology, Faculty of Science, Ehime University, 2-5, Bunkyo-Cho, Matsuyama, 790-8577, Japan.

Country: Japan

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Dev Growth Differ

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis Related Publications

• Analysis of where and which types of proteinases participate in lysosomal proteinase processing using bafilomycin A1 and Helicobacter pylori Vac A toxin.
• Anti-Sm autoantibodies cross-react with ribosomal protein S10: a common structural unit shared by the small nuclear RNP proteins and the ribosomal protein.
• Comprehensive proteomics analysis of autophagy-deficient mouse liver.
• Decreased lysosomal subunit c-degrading activity in fibroblasts from patients with late infantile neuronal ceroid lipofuscinosis.
• Effect of Bcl11b genotypes and gamma-radiation on the development of mouse thymic lymphomas.
• Fed-batch culture automated by uses of continuously measured cell concentration and culture volume.
• Formation of a triple-stranded DNA between d(GGA:TCC) repeats and d(GGA) repeat oligonucleotides.
• Function of the propeptide region in recombinant expression of active procathepsin L in Escherichia coli.
• Hemoprotein H-450 identified as a form of cytochrome P-450 having an endogenous ligand at the 6th coordination position of the heme.
• Initial observation of potential factors involved in the specification process of oral-aboral axis in the sand dollar Scaphechinus mirabilis.
• LC3 and Autophagy.
• Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation.
• Suppression of lysosomal proteolysis at three different steps in regenerating rat liver.
• Transcription of mouse ribosomal RNA gene with inactive extracts is activated by NAD+ in vitro.
• Tripeptidyl peptidase I, the late infantile neuronal ceroid lipofuscinosis gene product, initiates the lysosomal degradation of subunit c of ATP synthase.
• Two mouse hypervariable minisatellites: chromosomal location and simultaneous mutation.