Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants.

Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants. Research Abstract Details 

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Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants. Abstract Text:

T Nikaido,T Ohmoto,H Noguchi,T Kinoshita,H Saitoh,U Sankawa,

Hot aqueous extracts of medicinal plants used in oriental medicine were tested for their inhibitory effect on beef heart phosphodiesterase to detect biologically active compounds present therein. Of 222 samples tested 22 showed reproducible inhibition. cAMP phosphodiesterase inhibitors contained in ANEMARRHENA ASPHODELOIDES were identified as norlignans and their structure activity relationship was investigated; CIS-hinokiresinol, the main inhibitor exhibited a prolongation effect on hexobarbital sleeping time in mice.

Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants. Publishing Authors By Initials

T Nikaido,T Ohmoto,H Noguchi,T Kinoshita,H Saitoh,U Sankawa,

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Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Planta medica

VOLUME: 43

Page Numbers: 18-23

Journal Abbreviation: Planta Med.

ISSN: 0032-0943

DAY: 2

MONTH: Sep

YEAR: 1981

Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants. Information

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LANGUAGE: eng

NlmUniqueID: 66751

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Grant and Affiliation Information for Inhibitors of Cyclic AMP Phosphodiesterase in Medicinal Plants.

AFFILIATION: Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba, Japan.

Country: Germany

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MEDLINETA: Planta Med

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