Inhibition, spike threshold, and stimulus selectivity in primary visual cortex.

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Abstract Text:

Nicholas J Priebe,David Ferster,

Ever since Hubel and Wiesel described orientation selectivity in the visual cortex, the question of how precise selectivity emerges has been marked by considerable debate. There are essentially two views of how selectivity arises. Feed-forward models rely entirely on the organization of thalamocortical inputs. Feedback models rely on lateral inhibition to refine selectivity relative to a weak bias provided by thalamocortical inputs. The debate is driven by two divergent lines of evidence. On the one hand, many response properties appear to require lateral inhibition, including precise orientation and direction selectivity and crossorientation suppression. On the other hand, intracellular recordings have failed to find consistent evidence for lateral inhibition. Here we demonstrate a resolution to this paradox. Feed-forward models incorporating the intrinsic nonlinear properties of cortical neurons and feed-forward circuits (i.e., spike threshold, contrast saturation, and spike-rate rectification) can account for properties that have previously appeared to require lateral inhibition.

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Publishing Authors By Initials

NJ Priebe,D Ferster,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neuron

VOLUME: 57

Page Numbers: 482-97

Journal Abbreviation: Neuron

ISSN: 0896-6273

DAY: 28

MONTH: Feb

YEAR: 2008

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8809320

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Inhibition, spike threshold, and stimulus selectivity in primary visual cortex. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Inhibition, spike threshold, and stimulus selectivity in primary visual cortex.

AFFILIATION: Section of Neurobiology, The University of Texas at Austin, 1 University Station C0920, Austin, TX 78712, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neuron

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Inhibition, spike threshold, and stimulus selectivity in primary visual cortex Related Publications

• Computational diversity in complex cells of cat primary visual cortex.
• Inhibition, spike threshold, and stimulus selectivity in primary visual cortex.
• Magnetic resonance imaging and angiography in cerebral fungal vasculitis.
• Matched-related donor transplantation for sickle cell disease: report from the Center for International Blood and Transplant Research.
• The emergence of contrast-invariant orientation tuning in simple cells of cat visual cortex.
• Use of hydroxyurea in prevention of stroke in children with sickle cell disease.