Inhibition of visceral protein synthesis by certain amino acid supplements.

Inhibition of visceral protein synthesis by certain amino acid supplements. Research Abstract Details 

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Inhibition of visceral protein synthesis by certain amino acid supplements. Abstract Text:

S Schwartz,A L Andreu,E Garcia,M Farriol,J Lopez,M A Arbos,

This study was focused on the effects produced by diets with different amino acid proportions on visceral protein synthesis (liver and jejunal mucosa). Eight groups of rats received an enteral modular diet supplemented with different amino acids (Group 1: Ile, Leu, Val; Group 2: Phe, Met, Gly; Group 3: Glu, Arg, Gly; Group 4: Gly, Group 5: Orn-Asp, Cys, Pro; Group 6: Lys, Ser, Thr; Group 7: Tyr, His, Ala). Group 8 was the control group. Rats were fed for four days. At the end of this period a flooding dose of 14C-Leu was injected and animals were killed. Liver and jejunal mucosa were removed and protein synthesis rate was determined. Results show a decreased liver protein synthesis in group fed with aromatic amino acids (53.8 +/- 8.4 vs. 88.6 +/- 12.1) and Glu-Arg (68.6 +/- 10.9). In jejunal mucosa there was a decrease of protein synthesis in groups fed with aromatic amino acids (98.7 +/- 16 vs 160.5 +/- 49). These changes seem to be related to the intracellular amino acid pool size and its influence on protein metabolism.

Inhibition of visceral protein synthesis by certain amino acid supplements. Publishing Authors By Initials

S Schwartz,AL Andreu,E Garcia,M Farriol,J Lopez,MA Arbos,

For similar body regions: viscera research abstracts see: body regions: viscera research

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Inhibition of visceral protein synthesis by certain amino acid supplements. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Physiological research / Academia Scientiarum Bohe

VOLUME: 42

Page Numbers: 347-50

Journal Abbreviation: Physiol Res

ISSN: 0862-8408

DAY: 2

MONTH: 04

YEAR: 1993

Inhibition of visceral protein synthesis by certain amino acid supplements. Information

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LANGUAGE: eng

NlmUniqueID: 9112413

Inhibition of visceral protein synthesis by certain amino acid supplements. Keywords Mesh Terms:

KEYWORDS: Viscera

MESH TERMS: metabolism

Chemical & Substance for Abstract: Inhibition of visceral protein synthesis by certain amino acid supplements. Information

Substance Name: Amino Acids

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Grant and Affiliation Information for Inhibition of visceral protein synthesis by certain amino acid supplements.

AFFILIATION: Research Unit Santiago Grisolía, Hospital Vall d'Hebrón, Barcelona, Spain.

Country: CZECH REPUBLIC

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MEDLINETA: Physiol Res

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