Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice.

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Abstract Text:

Shamee Bhattacharjee,Tapasi Rana,Archana Sengupta,

Globally, colorectal cancer is the third commonest cancer in men since 1975.The present study focuses on the preventive strategies aimed at reducing the incidences and mortality of large bowel cancer. Chemoprevention of colon cancer appears to be a very realistic possibility because various intermediate stages have been identified preceding the development of malignant colonic tumors. Several studies have demonstrated that generous consumption of vegetables reduces the risk of colon cancer. This idea has prompted the present investigation to search for some novel plant products, which may have possible anticarcinogenic activity. It has already been proved from various experiments that chemopreventive agents, by virtue of their anti-oxidant, anti-inflammatory, anti-proliferative, apoptosis-inducing activity, act at various levels including molecular, cellular, tissue and organ levels to interfere with carcinogens. Previous studies from our laboratory have already reported the inhibitory effect of cinnamon and cardamom on azoxymethane induced colon carcinogenesis by virtue of their anti-inflammatory, anti-proliferative and pro-apoptotic activity. This particular experiment was carried out to assess the anti-oxidative potential of these spices. Aqueous suspensions of cinnamon and cardamom have been shown to enhance the level of detoxifying enzyme (GST activity) with simultaneous decrease in lipid peroxidation levels in the treatment groups when compared to that of the carcinogen control group.

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Publishing Authors By Initials

S Bhattacharjee,T Rana,A Sengupta,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE: 2007 Oct-Dec

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Asian Pacific journal of cancer prevention : APJCP

VOLUME: 8

Page Numbers: 578-82

Journal Abbreviation: Asian Pac. J. Cancer Prev.

ISSN: 1513-7368

DAY: 11

MONTH: 02

YEAR: 2008

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101130625

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice.

AFFILIATION: Dept. of Cancer Chemoprevention, Chittaranjan National Cancer Institute, 37, S. P. Mukherjee Road, Kolkata-700026, India E-mail: archana_sen@yahoo.com.

Country: Thailand

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Asian Pac J Cancer Prev

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice Related Publications

• 7-Substituted actinomycin D (NSC-3053) analogs as fluorescent DNA-binding and experimental antitumor agents.
• BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination.
• Burkitt's lymphoma in Jamaica. Report of the first case with cytological, histochemical and electron microscopic studies.
• Cervical vertebrae anomalies-incidental findings on lateral cephalograms.
• Chronic cervical lymphadenopathy.
• Clinical aspects of defective luteal phase and its treatment with cyclofenil.
• Conservation of average hydrophobicity of apolar aminoacids in polypeptides constituting same glycosyl hydrolase sub-family enzymes.
• Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment.
• Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans.
• Effect of beta-cyclodextrin nanocavity confinement on the photophysics of robinetin.
• Effect of reflux-induced inflammation on transient receptor potential vanilloid one (TRPV1) expression in primary sensory neurons innervating the oesophagus of rats.
• Effects of the 5-HT3 receptor antagonist, alosetron, in a rat model of somatic and visceral hyperalgesia.
• Epigenetic chromatin silencing: bistability and front propagation.
• Fluctuations at a constrained liquid-solid interface.
• Histochemical and morphological examination of proliferation and apoptosis in human first trimester villous trophoblast.
• Increased level of urinary nitric oxide metabolites in leprosy patients during type 2 reactions and decreased after antireactional therapy.
• Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamon During Chemically Induced Colon Carcinogenesis in Swiss Albino Mice.
• Interaction of 7-hydroxyflavone with human serum albumin: A spectroscopic study.
• Modulation of vesicle adhesion and spreading kinetics by hyaluronan cushions.
• Nature and occurrences of pesticidal deaths in India (1960-2005) for analytical consideration.
• Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination.
• Predisposition to HPV16/18-related cervical cancer because of proline homozygosity at codon 72 of p53 among Indian women is influenced by HLA-B*07 and homozygosity of HLA-DQB1*03.
• Shunting in the human kidney.
• Smell: the worm turns.
• The fate of transplants of articular cartilage in the rabbit.
• The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis.
• Tobacco proliferating cell nuclear antigen binds directly and stimulates both activity and processivity of ddNTP-sensitive mungbean DNA polymerase.
• Trans-acting factor designated OSBZ8 interacts with both typical abscisic acid responsive elements as well as abscisic acid responsive element-like sequences in the vegetative tissues of indica rice cultivars.
• Trans-oesophageal Echocardiography for Cardiac Anaesthesiologists: Part I.
• Trans-oesophageal Echocardiography for Cardiac Anaesthesiologists: Part II.