Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin.

Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Research Abstract Details 

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Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Abstract Text:

Infrared spectroscopy was used to trace active substances and ointment vehicles applied on the skin. Vaseline and lanoline could be traced after 8 hrs but not olive oil. From the active substances, ethyl-4-amino-benzoate (5 per cent), clioquinol (5 per cent), parabenes (15 per cent), 5,7-dichlor-8-hydroxy-2-methyl-chinolin (5 per cent), balsam of Peru (25 per cent) and pyroleum pini (12 per cent) could be traced 1 hr after application but had disappeared after 8 hrs. Ethylenediamine (1 per cent), chlorcresol (1 per cent), pyroleum lithantracis (5 per cent), were not traceable after 1 hr, and curiously neither neomycine sulphate in spite of its high concentration (20 per cent). The reaction of the skin surface lipids, after application of different substances, was deduced from the spectra. Clioquinol and pyroleum lithantracis seem to give rise to hydrolysis of the triglycerides, the free fatty acids being clearly identifiable. It is felt that infrared spectroscopy can be used as an effective method to trace different substances such as potent allergens on healthy or diseased skin.

Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Publishing Authors By Initials

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Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives for dermatological research. Archiv für d

VOLUME: 253

Page Numbers: 63-9

Journal Abbreviation:

ISSN: 0340-3696

DAY: 29

MONTH: Aug

YEAR: 1975

Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Information

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LANGUAGE: eng

NlmUniqueID: 7512589

Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Keywords Mesh Terms:

KEYWORDS: Tars

MESH TERMS: analysis

Chemical & Substance for Abstract: Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin. Information

Substance Name: Benzocaine

Registry Number: 94-09-7

Grant and Affiliation Information for Infrared spectroscopy for tracing of topically applied ointment vehicles and active substances on healthy skin.

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Country: GERMANY, WEST

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MEDLINETA: Arch Dermatol Res

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